L-threonate 3-dehydrogenase

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L-threonate 3-dehydrogenase
Identifiers
EC number1.1.1.129
CAS number37250-59-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a L-threonate 3-dehydrogenase (EC 1.1.1.129) is an enzyme that catalyzes the chemical reaction

L-threonate + NAD+ 3-dehydro-L-threonate + NADH + H+

Thus, the two substrates of this enzyme are L-threonate and NAD+, whereas its 3 products are 3-dehydro-L-threonate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-threonate:NAD+ 3-oxidoreductase. Other names in common use include threonate dehydrogenase, and L-threonic acid dehydrogenase. This enzyme participates in ascorbate and aldarate metabolism.

References[edit]

  • Aspen AJ, Jakoby WB (1964). "L-threonic Acid Dehydrogenase: Purification and Properties". J. Biol. Chem. 239: 710–3. PMID 14154441.