Methylhomatropine

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Homatropine methyl bromide
Methylhomatropinebromide.png
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ECHA InfoCard 100.001.168 Edit this at Wikidata
Chemical and physical data
Formula C17H24BrNO3
Molar mass 370.26 g/mol
3D model (JSmol)
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Homatropine methylbromide or methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. It is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It does not cross the blood–brain barrier. It is used to effectively relieve intestinal spasms and abdominal cramps, without producing the adverse effects of less specific anticholinergics.[1] It is used, in addition to papaverine, as a component of mild drugs that help "flush" the bile.

Certain preparations of drugs such as hydrocodone are mixed with a small, sub-therapeutic amount of homatropine methylbromide to discourage intentional overdose.[2]

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