Oxotremorine

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Oxotremorine
Oxotremorine.svg
Systematic (IUPAC) name
1-(4-Pyrrolidin-1-ylbut-2-yn-1-yl)pyrrolidin-2-one
Clinical data
Pregnancy
category
  • C
Legal status
  • US: Experimental/not yet approved
Routes of
administration
Oral, intravenous
Identifiers
CAS Registry Number 70-22-4 YesY
ATC code None
IUPHAR/BPS 302
ChemSpider 4469 N
ChEMBL CHEMBL7634 N
Chemical data
Formula C12H18N2O
Molecular mass 206.28
 N (what is this?)  (verify)

Oxotremorine is a parasympathomimetic drug that acts as a non-selective muscarinic acetylcholine receptor agonist.[1]

Oxotremorine produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs.[2]

Oxotremorine produces also antipsychotic effects.[3]

References[edit]

  1. ^ Tang C, Castoldi AF, Costa LG (April 1993). "Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes". Biochem. Mol. Biol. Int. 29 (6): 1047–54. PMID 8330013. 
  2. ^ Craig, C. R.; Stitzel, R. E. (2004). Modern Pharmacology. Boston: Little, Brown. p. 149. 
  3. ^ http://cat.inist.fr/?aModele=afficheN&cpsidt=20678587

See also[edit]