TSPAN2

From Wikipedia, the free encyclopedia
Jump to: navigation, search
TSPAN2
Identifiers
Aliases TSPAN2, NET3, TSN2, TSPAN-2, tetraspanin 2
External IDs MGI: 1917997 HomoloGene: 21169 GeneCards: TSPAN2
Gene location (Human)
Chromosome 1 (human)
Chr. Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for TSPAN2
Genomic location for TSPAN2
Band No data available Start 115,048,011 bp[1]
End 115,089,500 bp[1]
RNA expression pattern
PBB GE TSPAN2 214606 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001308315
NM_001308316
NM_005725

NM_001243132
NM_027533

RefSeq (protein)

NP_001295244
NP_001295245
NP_005716

NP_001230061
NP_081809

Location (UCSC) Chr 1: 115.05 – 115.09 Mb Chr 1: 102.73 – 102.8 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Tetraspanin-2 is a protein that in humans is encoded by the TSPAN2 gene.[5][6][7]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000134198 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027858 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Todd SC, Doctor VS, Levy S (Sep 1998). "Sequences and expression of six new members of the tetraspanin/TM4SF family". Biochim Biophys Acta. 1399 (1): 101–4. PMID 9714763. doi:10.1016/s0167-4781(98)00087-6. 
  6. ^ Berditchevski F (Dec 2001). "Complexes of tetraspanins with integrins: more than meets the eye". J Cell Sci. 114 (Pt 23): 4143–51. PMID 11739647. 
  7. ^ a b "Entrez Gene: TSPAN2 tetraspanin 2". 

Further reading[edit]

External links[edit]