TSPAN8

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TSPAN8
Identifiers
Aliases TSPAN8, CO-029, TM4SF3, tetraspanin 8
External IDs MGI: 2384918 HomoloGene: 20968 GeneCards: TSPAN8
RNA expression pattern
PBB GE TSPAN8 203824 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004616

NM_001168679
NM_001168680
NM_146010

RefSeq (protein)

NP_004607

Location (UCSC) Chr 12: 71.13 – 71.44 Mb Chr 10: 115.82 – 115.85 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Tetraspanin-8 is a protein that in humans is encoded by the TSPAN8 gene.[3][4]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.[4]

References[edit]

Further reading[edit]