MS4A7

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MS4A7
Identifiers
Aliases MS4A7, 4SPAN2, CD20L4, CFFM4, MS4A8, membrane spanning 4-domains A7
External IDs MGI: 1918846 HomoloGene: 10922 GeneCards: MS4A7
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_206940
NM_021201
NM_206938
NM_206939

NM_001025610
NM_001276398
NM_027836

RefSeq (protein)

NP_067024
NP_996821
NP_996822
NP_996823

n/a

Location (UCSC) Chr 11: 60.38 – 60.4 Mb Chr 19: 11.32 – 11.34 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Membrane-spanning 4-domains subfamily A member 7 is a protein that in humans is encoded by the MS4A7 gene.[3][4][5]

This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Ishibashi K, Suzuki M, Sasaki S, Imai M (Mar 2001). "Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor". Gene. 264 (1): 87–93. doi:10.1016/S0378-1119(00)00598-9. PMID 11245982. 
  4. ^ Liang Y, Tedder TF (Jun 2001). "Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse". Genomics. 72 (2): 119–27. doi:10.1006/geno.2000.6472. PMID 11401424. 
  5. ^ a b "Entrez Gene: MS4A7 membrane-spanning 4-domains, subfamily A, member 7". 

Further reading[edit]