Thottapalayam virus

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Thottapalayam virus
Virus classification
Group: Group V ((−)ssRNA)
Order: Unassigned
Family: Bunyaviridae
Genus: Hantavirus
Species: Thottapalayam virus

Thottapalayam virus (TMPV) is single-stranded, enveloped, negative-sense RNA virus species of the genus hantavirus in the Bunyaviridae family. It is the first hantavirus to be isolated from a shrew. It was discovered in India in 1964. [1][2]

Natural reservoir[edit]

TPMV was first isolated from an Asian house shrew (Suncus murinus) in India in 1964. It is the only known hantavirus to be hosted by a shrew instead of a rodent. It was subsequently isolated in Asian house shrews in Wenzhou of Zhejiang province, China. [3]

Virology[edit]

Phylogenetic analysis has shown that Thottapalayam virus, and its closely related strains, is unique and forms a distinct lineage, unrelated to other hantaviruses. The closest hantavirus to TMPV is Imjin virus which demonstrates corresponding nucleotide sequences to TPMV as does Tanganya virus.[4]

See also[edit]

References[edit]

  1. ^ Carey DE, Reuben R, Panicker KN, Shope RE, Myers RM. Thottapalayam virus: a presumptive arbovirus isolated from a shrew in India. Indian J Med Res. 1971;59:1758–60.
  2. ^ Serge Morand, François Beaudeau, Jacques Cabaret.New Frontiers of Molecular Epidemiology of Infectious Diseases. Springer, Sep 8, 2011. pp. 198-199.
  3. ^ Wen-Ping Guo, Xian-Dan Lin, Wen Wang, Xiao-He Zhang, Yi Chen, Jian-Hai Cao, Qing-Xiang Ni, Wang-Cang Li, Ming-Hui Li, Alexander Plyusnin, Yong-Zhen Zhang. A new subtype of Thottapalayam virus carried by the Asian house shrew (Suncus murinus) in China. Infection, genetics and evolution: journal of molecular epidemiology and evolutionary genetics in infectious diseases (Impact Factor: 3.22). 07/2011; 11(8):1862-7.
  4. ^ Wen-Ping Guo, Xian-Dan Lin, Wen Wang, Xiao-He Zhang, Yi Chen, Jian-Hai Cao, Qing-Xiang Ni, Wang-Cang Li, Ming-Hui Li, Alexander Plyusnin, Yong-Zhen Zhang. A new subtype of Thottapalayam virus carried by the Asian house shrew (Suncus murinus) in China. Infection, genetics and evolution: journal of molecular epidemiology and evolutionary genetics in infectious diseases (Impact Factor: 3.22). 07/2011; 11(8):1862-7.

External links[edit]