OR6N1

OR6N1
Identifiers
Aliases	OR6N1, OR1-22, olfactory receptor family 6 subfamily N member 1
External IDs	MGI: 3030263; HomoloGene: 17366; GeneCards: OR6N1; OMA:OR6N1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1q23.1 Start 158,747,814 bp End 158,772,195 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1|1 H3 Start 173,911,897 bp End 173,918,909 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bone marrow granulocyte bone marrow cells blood monocyte upper lobe of left lung right testis left testis spleen right lung Top expressed in respiratory epithelium nasal epithelium peripheral nervous system olfactory epithelium More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 128372 258717 Ensembl ENSG00000197403 ENSMUSG00000049528 UniProt Q8NGY5 n/a RefSeq (mRNA) NM_001005185 NM_146722 RefSeq (protein) NP_001005185 n/a Location (UCSC) Chr 1: 158.75 – 158.77 Mb Chr 1: 173.91 – 173.92 Mb PubMed search
Wikidata
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Olfactory receptor 6N1 is a protein that in humans is encoded by the OR6N1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.

External links

• OR6N1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.