Protein-glucosylgalactosylhydroxylysine glucosidase
| protein-glucosylgalactosylhydroxylysine glucosidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.2.1.107 | ||||||||
| CAS no. | 72829-45-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) is an enzyme that catalyzes the chemical reaction
- protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine + H2O D-glucose + protein beta-D-galactosyl-L-hydroxylysine
Thus, the two substrates of this enzyme are protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine and H2O, whereas its two products are D-glucose and protein beta-D-galactosyl-L-hydroxylysine.
This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase. Other names in common use include 2-O-alpha-D-glucopyranosyl-5-O-alpha-D-galactopyranosylhydroxy-L-, and lysine glucohydrolase.
References
- Hamazaki H, Hotta K (1979). "Purification and characterization of an alpha-glucosidase specific for hydroxylysine-linked disaccharide of collagen". J. Biol. Chem. 254 (19): 9682–7. PMID 385589.
- Hamazaki H, Hotta K (1980). "Enzymatic hydrolysis of disaccharide unit of collagen. Isolation of 2-O-alpha-D-glucopyranosyl-O-beta-D-galactopyranosyl-hydroxylysine glucohydrolase from rat spleens". Eur. J. Biochem. 111 (2): 587–91. doi:10.1111/j.1432-1033.1980.tb04975.x. PMID 7460918.
- Sternberg M, Spiro RG (1979). "Studies on the catabolism of the hydroxylysine-linked disaccharide units of basement membranes and collagens. Isolation and characterization of a rat kidney alpha-glucosidase of high specificity". J. Biol. Chem. 254 (20): 10329–36. PMID 385599.
