The season saw the introduction of a new engine package. The Honda CBR600RRinline-4 engine package, which was used since the inaugural season of Moto2 in 2010, was replaced by a 765 cc (46.7 cu in) inline-3 engine manufacturered by Triumph Motorcycles. It is based on the engine of the Triumph Street Triple RS 765. Due to availability constraints on the new Moto2 2019 engine, and the fact that there will be no machines of this specification in other championships, it was agreed that Moto2 wildcard entries will not be available in 2019.[1]
This class and Moto3 also adopted the qualifying format used by MotoGP for the season, in which the riders that placed 15th or lower on combined times in the third free practice session would be admitted to qualifying 1, then the four fastest riders from that session would join the fastest 14 riders in qualifying 2.
Tech 3 switched manufacturers to KTM in line with their switch to KTM bikes in the MotoGP class, after having previously competed in Moto2 with their own chassis.[31]
MV Agusta returned to Grand Prix motorcycle racing after being absent for 42 years, joining forces with Forward Racing to compete in Moto2. This results in Suter's withdrawal from Moto2.
Tasca Racing Scuderia Moto2 downsized to one bike again after having previously competed with two bikes in the 2018 season.[32]
Marinelli Snipers Team withdrew from Moto2.
Ángel Nieto Team expanded its operations to field two bikes in Moto2.
Sam Lowes left Swiss Innovative Investors team to return to Gresini Racing. Lowes previously competed with Gresini Racing in the 2016 Moto2 & 2017 MotoGP seasons. His seat was taken by Joe Roberts.
Jake Dixon will make his full season debut with Ángel Nieto Team. He was partnered with Xavi Cardelús, who will make his full season debut in Moto2 after he previously made some Moto2 appearances in the 2018 season as a wildcard & replacement rider.
Simone Corsi was dropped by Tasca Racing due to poor results and replaced by Mattia Pasini from the Czech GP onwards.
Steven Odendaal was dropped from NTS RW Racing GP after the British GP. Simone Corsi was his replacement for the San Marino and Aragon GP, who was then replaced by Jesko Raffin from the Thailand GP onwards. Raffin also filled in for Odendaal in the first three races of the season, due to injury.