Flubendazole

Flubendazole
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	P02CA05 (WHO) QP52AC12 (WHO);
Identifiers
	IUPAC name Methyl N-[6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate;
CAS Number	31430-15-6 ;
PubChem CID	35802;
DrugBank	DB08974 ;
ChemSpider	32932 ;
UNII	R8M46911LR;
KEGG	D04200 ;
ChEBI	CHEBI:77095 ;
ChEMBL	ChEMBL145946 ;
CompTox Dashboard (EPA)	DTXSID8023058 ;
ECHA InfoCard	100.046.007
Chemical and physical data
Formula	C16H12FN3O3
Molar mass	313.28 g/mol g·mol−1
3D model (JSmol)	Interactive image;
Melting point	260 °C (500 °F)
	SMILES COC(=O)Nc1[nH]c2ccc(cc2n1)C(=O)c3ccc(cc3)F;
	InChI InChI=1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22) ; Key:CPEUVMUXAHMANV-UHFFFAOYSA-N ;
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Flubendazole is an anthelmintic. Its brand name is Flutelmium which is a paste manufactured by Janssen Pharmaceutica N.V. used by veterinarians for protection against internal parasites and worms in dogs and cats. Other brand names are Flubenol, Biovermin, and Flumoxal.^[1]

It is also available for human use to treat worm infections. It is available OTC (without prescription) in Europe. Flubendazole-treated grit is used on UK grouse-shooting moors to reduce impact on the bird numbers from strongyle worm. Evidence of high worm burden is required before a veterinarian can dispense and sell the product, known as 'medicated grit'.^[2]

References

^ US Patent 5824336 - Chewable flubendazole tablets for companion animals
^ "Best practice use of medicated grit". Game and Wildlife Conservation Trust. Retrieved 27 September 2016.

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[1] US Patent 5824336 - Chewable flubendazole tablets for companion animals

[2] "Best practice use of medicated grit". Game and Wildlife Conservation Trust. Retrieved 27 September 2016.

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See also

References