Glucan 1,4-α-glucosidase
| Glucan 1,4-alpha-glucosidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.2.1.3 | ||||||||
| CAS no. | 9032-08-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Glucan 1,4-alpha-glucosidase (EC 3.2.1.3, glucoamylase, amyloglucosidase, gamma-amylase, lysosomal alpha-glucosidase, acid maltase, exo-1,4-alpha-glucosidase, glucose amylase, gamma-1,4-glucan glucohydrolase, acid maltase, 1,4-alpha-D-glucan glucohydrolase) is an enzyme located on the brush border of the small intestine with systematic name 4-alpha-D-glucan glucohydrolase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose
Most forms of the enzyme can rapidly hydrolyse 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4.
See also
References
- ^ French, D. and Knapp, D.W. (1950). "The maltase of Clostridium acetobutylicum". J. Biol. Chem. 187: 463–471. PMID 14803428.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Illingworth Brown, B. and Brown, D.H. (1965). "The subcellular distribution of enzymes in type II glycogenosis and the occurrence of an oligo-α-1,4-glucan glucohydrolase in human tissues". Biochim. Biophys. Acta. 110: 124–133. doi:10.1016/s0926-6593(65)80101-1. PMID 4286143.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Jeffrey, P.L., Brown, D.H. and Brown, B.I. (1970). "Studies of lysosomal α-glucosidase. I. Purification and properties of the rat liver enzyme". Biochemistry. 9: 1403–1415. doi:10.1021/bi00808a015. PMID 4313883.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Kelly, J.J. and Alpers, D.H. (1973). "Properties of human intestinal glucoamylase". Biochim. Biophys. Acta. 315: 113–122. doi:10.1016/0005-2744(73)90135-6. PMID 4743896.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Miller, K.D. and Copeland, W.H. (1956). "A blood trans-α-glucosylase". Biochim. Biophys. Acta. 22: 193–194. doi:10.1016/0006-3002(56)90242-6. PMID 13373867.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Tsujisaka, Y., Fukimoto, J. and Yamamoto, T. (1958). "Specificity of crystalline saccharogenic amylase of moulds". Nature. 181: 770–771. doi:10.1038/181770a0. PMID 13517301.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
External links
- Glucan+1,4-alpha-glucosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)