Isopropanol dehydrogenase (NADP+)

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
isopropanol dehydrogenase (NADP+)
Identifiers
EC number1.1.1.80
CAS number37250-18-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, an isopropanol dehydrogenase (NADP+) (EC 1.1.1.80) is an enzyme that catalyzes the chemical reaction

propan-2-ol + NADP+ acetone + NADPH + H+

Thus, the two substrates of this enzyme are propan-2-ol and NADP+, whereas its 3 products are acetone, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is propan-2-ol:NADP+ oxidoreductase. This enzyme is also called isopropanol dehydrogenase (NADP+). This enzyme participates in propanoate metabolism.

References[edit]

  • Hoshino K (1960). "Organism producing isopropanol from acetone. V. Enzymological [studies] on the oxidation-reduction of Lactobacillus brevis var. hofuensis". Nippon Nogei Kagaku Kaishi (in Japanese). 34: 608–615.
  • Hoshino K, Udagawa K (1960). "Organism producing isopropanol from acetone. VI. Isopropanol dehydrogenase and alcohol dehydrogenase of Lactobacillus brevis var. hofuensis". Nippon Nogei Kagaku Kaishi (in Japanese). 34: 616–619.