NLRP14

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NLRP14
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases NLRP14, CLR11.2, GC-LRR, NALP14, NOD5, PAN8, NLR family, pyrin domain containing 14, NLR family pyrin domain containing 14
External IDs MGI: 1924108 HomoloGene: 18531 GeneCards: NLRP14
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_176822

NM_001002894

RefSeq (protein)

NP_789792

NP_001002894.2
NP_001002894

Location (UCSC) Chr 11: 7.02 – 7.07 Mb Chr 7: 107.17 – 107.2 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

NLRP14, short for NOD-like receptor family pyrin domain containing 14, is an intracellular protein of mammals associated with a role in spermatogenesis. It is also known as NALP14, NOD5, GC-LRR, Nalp-iota, PAN8, and CLR11.2, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.[3] NLRP14 is found exclusively in the testes where it is expressed within spermatogonia, spermatocytes and spermatids.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Tschopp J, Martinon F, Burns K (February 2003). "NALPs: a novel protein family involved in inflammation". Nat. Rev. Mol. Cell Biol. 4 (2): 95–104. doi:10.1038/nrm1019. PMID 12563287. 
  4. ^ Westerveld GH, Korver CM, van Pelt AM, et al. (December 2006). "Mutations in the testis-specific NALP14 gene in men suffering from spermatogenic failure". Hum. Reprod. 21 (12): 3178–84. doi:10.1093/humrep/del293. PMID 16931801. 

Further reading[edit]