OR4Q3

OR4Q3
Identifiers
Aliases	OR4Q3, C14orf13, HSA6, OR14-3, OR4Q4, c14_5008, olfactory receptor family 4 subfamily Q member 3
External IDs	MGI: 3030569; HomoloGene: 71977; GeneCards: OR4Q3; OMA:OR4Q3 - orthologs
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 C1 Start 50,580,069 bp End 50,586,329 bp
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 441669 257909 Ensembl n/a ENSMUSG00000046210 UniProt Q8NH05 Q7TRM4 RefSeq (mRNA) NM_172194 NM_001405963 NM_001011754 RefSeq (protein) NP_751944 NP_001011754 Location (UCSC) n/a Chr 14: 50.58 – 50.59 Mb PubMed search
Wikidata
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Olfactory receptor 4Q3 is a protein that in humans is encoded by the OR4Q3 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. Bibcode:2000PNAS...97.2870R. doi:10.1073/pnas.040580197. PMC 16022. PMID 10706615.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4Q3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.