DNA polymerase epsilon

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DNA-directed DNA polymerase
Identifiers
EC number 2.7.7.7
CAS number 9012-90-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

DNA polymerase epsilon is a member of the DNA polymerase family of enzymes. It is composed of the following four subunits: POLE (central catalytic unit), POLE2 (subunit 2), POLE3 (subunit 3), and POLE4 (subunit 4). Recent evidence suggests that it plays a mayor role in leading strand DNA synthesis and nucleotide and base excision repair.[1][2]

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