Haplogroup CZ (mtDNA)

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Haplogroup CZ
Possible time of origin
Possible place of origin
Ancestor M8
Descendants C, Z
Defining mutations 249d[1]

In human mitochondrial genetics, Haplogroup CZ is a human mitochondrial DNA (mtDNA) haplogroup.


Haplogroup CZ is a descendant of haplogroup M and is a parent to haplogroups C and Z. Haplogroup CZ is divided into subclades C and Z, which share a common ancestor approximately 45,000 years ago.[2]


Today CZ is found in eastern Eurasian populations. It is most common in Siberian populations. It is recognized by the genetic marker at 249d.



This phylogenetic tree of haplogroup CZ subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[1] and subsequent published research.

  • M
    • CZ
      • C
      • Z

See also[edit]

Evolutionary tree of human mitochondrial DNA (mtDNA) haplogroups

  Mitochondrial Eve (L)    
L0 L1–6
L1 L2 L3   L4 L5 L6
  M N  
CZ D E G Q   A S   R   I W X Y
C Z B F R0   pre-JT P  U


  1. ^ a b van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation 30 (2): E386–E394. doi:10.1002/humu.20921. PMID 18853457. Retrieved 2009-05-20. 
  2. ^ Sebastian Lippold, Hongyang Xu, Albert Ko et al. (2014), "Human paternal and maternal demographic histories: insights from high-resolution Y chromosome and mtDNA sequences." bioRxiv doi: 10.1101/001792

External links[edit]