OR5AU1

OR5AU1
Identifiers
Aliases	OR5AU1, olfactory receptor, family 5, subfamily AU, member 1, OR14-38, olfactory receptor family 5 subfamily AU member 1
External IDs	MGI: 3030055; HomoloGene: 45823; GeneCards: OR5AU1; OMA:OR5AU1 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q11.2 Start 21,148,370 bp End 21,159,060 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 C2 Start 52,271,419 bp End 52,279,916 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in blood olfactory zone of nasal mucosa Top expressed in zygote secondary oocyte primary oocyte embryo blastocyst More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390445 258420 Ensembl ENSG00000169327 ENSMUSG00000044286 UniProt Q8NGC0 B2RVX8 RefSeq (mRNA) NM_001004731 NM_001001808 NM_146428 RefSeq (protein) NP_001004731 NP_001001808 Location (UCSC) Chr 14: 21.15 – 21.16 Mb Chr 14: 52.27 – 52.28 Mb PubMed search
Wikidata
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Olfactory receptor 5AU1 is a protein that in humans is encoded by the OR5AU1 gene.

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (September 2002). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (February 2004). "The human olfactory receptor gene family". Proceedings of the National Academy of Sciences of the United States of America. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5AU1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.