OR4N5

OR4N5
Identifiers
Aliases	OR4N5, olfactory receptor family 4 subfamily N member 5
External IDs	MGI: 3030556; HomoloGene: 17270; GeneCards: OR4N5; OMA:OR4N5 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q11.2 Start 20,138,820 bp End 20,145,471 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 C1 Start 50,131,715 bp End 50,139,456 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390437 258487 Ensembl ENSG00000184394 ENSMUSG00000048933 UniProt Q8IXE1 Q8VFC8 RefSeq (mRNA) NM_001004724 NM_146494 RefSeq (protein) NP_001004724 NP_666705 Location (UCSC) Chr 14: 20.14 – 20.15 Mb Chr 14: 50.13 – 50.14 Mb PubMed search
Wikidata
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Olfactory receptor 4N5 is a protein that in humans is encoded by the OR4N5 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4N5+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.