Civil Hospital Karachi is a 1,900-bed tertiary care public hospital that imparts both undergraduate and postgraduate teaching and training. It is one of the teaching hospitals affiliated with the Dow Medical College now the Dow University of Health Sciences. Civil Hospital Karachi is arguably the largest teaching hospital of Pakistan, catering not only to all areas of the province of Sindh but also the neighboring province of Balochistan as well.
The Civil Hospital Karachi was founded in 1898 in the wake of a third pandemic of Bubonic Plague on the one hand, and the platinum jubilee of Queen Victoria on the other. The pandemic would kill at least an estimated 10 million people in India alone over a period of 20 years. It is important to mention the status of Karachi at that time. Being the port city, Karachi was the business, military and nerve center of Sindh right from the start. Towards the close of the nineteenth century, Karachi emerged as the cleanest city towards this side of the Suez Canal, with an estimated population of 105,000 which continued to grow in view of its strategic importance. Lord Curzon the Viceroy of India visited Civil Hospital Karachi in 1900 and unveiled a commemorative plaque to mark the platinum jubilee of Queen Victoria. The plaque is placed in the same spot, which was initially a nursing school and subsequently transformed into a state-of-the-art Burns Center in what is known till today as the Victoria Block or the Jubilee Block, while the entire building is heritage-protected by the provincial Department of Culture allowing for repairs and renovation but eschewing any structural change in its original design. The Civil Hospital Karachi continued to function efficiently until independence as the principal hospital of Karachi and received tremendous impetus after 1945 when the then Governor of Sindh Sir Hugh Dow transferred the medical school provisionally recognized by the Bombay University from Hyderabad to Karachi and laid the foundation of the Dow Medical College in its present location on 10 December 1945, with the Civil Hospital Karachi attached to it as a teaching hospital. The creation of a new state of Pakistan brought with it the need for a massive relief and rehabilitation efforts for hundreds of thousands of refugees pouring in from India and addressing all their basic needs including health needs through a largely inadequate and unprepared system. A visitor’s book maintained during the late fifties and early sixties indicates that the Civil Hospital Karachi was frequented by several dignitaries such as government ministers, ambassadors and eminent personalities visiting Pakistan. A 1961 entry by Lady Bird Johnson then spouse of the Vice President of the USA is particularly revealing: It reads: "This has been a visit both heart-breaking and rewarding. My hat is off to you women doctors!"  This indicates that health care professionals have been up against tremendous odds over the last few decades.
Organization and management
After the creation of Pakistan in 1947, Karachi became the capital of the new state, both the medical college and its teaching hospital came under the jurisdiction of the provincial government of Sindh (or West Pakistan from 1955–1970). Initially after independence, Col Aziz K M Khan, Principal of Dow Medical College was made administrator of the Civil Hospital Karachi. However in 1949, the post was bifurcated in view of its growing workload, and Dr Ali Ahmed S Kazi was named as the first Medical Superintendent of the hospital. He established a system of good governance in the hospital and was assisted by a team of senior academicians and hospital administrators prior to his posting as Director Health Services Sindh a few years later. Over the years a few other administrators such as Prof Mahmud Ali Shah and Prof Shamsuddin H Rahimtoola were assigned both the positions of Principal Dow Medical College and Medical Superintendent Civil Hospital Karachi in an effort to better coordinate the functions on the campus. However after the upgradation of the Dow Medical College into the Dow University of Health Sciences a few years ago, there is a clear cut demarcation between the hospital’s academic and administrative responsibilities. Dr. Jamil Ahmed Siddiqui is the current Medical Superintendent of Civil Hospital Karachi.
Initially established in 1898 with 250 beds to provide basic health facilities, the hospital has expanded considerably and has been totally transformed over the years. Its 1,900 beds are located in 34 department, with over a dozen major operation theaters and a huge out patient attendance. Greater stress is being laid on public-private partnerships and preventive work notably in the Paediatrics department to avert unnecessary infant and child deaths due to pneumonia, malnutrition, diarrhea or vaccine-preventable illnesses. Measures are also in place to prevent and control major communicable diseases such as Tuberculosis, Malaria, viral Hepatitis B & C and HIV/AIDS, in addition to non-communicable diseases such as cardiovascular diseases, diabetes and cancers having a huge burden in Pakistan. Today as Karachi is a sprawling mega-city with a population estimated at 14 million divided into 18 major towns, the Civil Hospital Karachi lives on to tell two tales in the same city. The services of this tertiary care institution has kept in line with the latest technological advances as far as that is compatible with the situation in a low-income developing country. Sophisticated laboratory and radiographical procedures, investigations and examinations are performed totally free to benefit the poor patients attending the hospital. An average of two million out-patients report to the hospital annually; 95% of which are non-affording patients entailing a huge cost on medicines, laboratory facilities and other logistics.
The clinical departments of the hospital include Internal Medicine, Gynaecology and Obstetrics, Anesthesiology, Pediatrics, Cardiac Surgery, Oncology, Radiology, General Surgery, Neuro Surgery and Laboratory Civil Hospital is proving all the services and facilities in one premise. The first state-of-the-art Burns unit has also been established in this hospital. The department of surgery comprises six general surgical units besides the specialties of neurosurgery, paediatric surgery, orthopedic surgery, urology, vascular surgery, maxillo-facial surgery and plastic surgery. The department of medicine comprises five general medicine units, 60 beds each. Other specialties includes Cardiology, Psychiatry, Dermatology, Neurology and Nephrology. The Department of Paediatrics has three units with a DTU (Diarrhea Treatment Unit). The Department of Gynaecology and Obstetrics is divided into three units, having facilities of labour room and Operation Theatre. The Emergency department has several sections including an Operation Theatre and Surgical Intensive Care Unit, which are functional around the clock for use in case of mass disasters. All the units function independently.
- A background to Dow Medical College 
- Visitors' Book of Civil Hospital Karachi, 1959–1965.
- HASAN MANSOOR. "14-storey trauma centre in CHK inaugurated". DAWN. Retrieved 19 October 2016.
- "SMBB AE&TC and AS Complex". Civil Hospital Karachi. Retrieved 19 October 2016.
- Experiences of a major bomb blast disaster