Clomegestone

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Clomegestone
Identifiers
  • (8R,9S,10R,13S,14S,16R,17R)-17-acetyl-6-chloro-17-hydroxy-10,13,16-trimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H29ClO3
Molar mass376.91686 g/mol g·mol−1
3D model (JSmol)
  • CC1CC2C3C=C(C4=CC(=O)CCC4(C3CCC2(C1(C(=O)C)O)C)C)Cl
  • InChI=InChI=1S/C22H29ClO3/c1-12-9-17-15-11-19(23)18-10-14(25)5-7-20(18,3)16(15)6-8-21(17,4)22(12,26)13(2)24/h10-12,15-17,26H,5-9H2,1-4H3/t12-,15-,16+,17+,20-,21+,22+/m1/s1
  • Key:GQBSINXSPAZDSK-ROXMKHFISA-N

Clomegestone (INN), also known as 6-chloro-17α-hydroxy-16α-methylpregna-4,6-diene-3,20-dione, is a steroidal progestin of the 17α-hydroxyprogesterone group that was never marketed.[1][2] An acetate ester, clomegestone acetate, also exists, and similarly was never marketed.[1]

References

  1. ^ a b J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 297–. ISBN 978-1-4757-2085-3.
  2. ^ World Health Organization (2013), The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances (PDF), p. 65



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