Norvinisterone
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| Trade names | Nor-Progestelea |
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| Synonyms | Neoprogestin, vinylnortestosterone, SC-4641 |
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| Formula | C20H28O2 |
| Molar mass | 300.435 g/mol |
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| Melting point | 169 to 171 °C (336 to 340 °F) [1] |
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Norvinisterone (INN) (marketed as Neoprogestin and Nor-Progestelea by Syntex; former developmental code name SC-4641), also known as 17α-vinyl-19-nortestosterone (or vinylnortestosterone), is a steroidal progestin and anabolic-androgenic steroid (AAS) of the 19-nortestosterone group that is or has been used in Europe.[1][2][3][4][5] It was synthesized in 1953,[2] and was studied in humans by 1960.[6] It appears to be quite androgenic, with about one-third and one-fifth of the androgenic and anabolic activity, respectively, of nandrolone (19-nortestosterone) in animal bioassays.[7]
See also[edit]
References[edit]
- ^ a b Merck Index, 11th edition, 6637
- ^ a b J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 889–. ISBN 978-1-4757-2085-3.
- ^ Pei-Show Juo (21 December 2001). Concise Dictionary of Biomedicine and Molecular Biology. CRC Press. pp. 774–. ISBN 978-1-4200-4130-9.
- ^ P. H. List; L. Hörhammer (12 March 2013). Chemikalien und Drogen Teil A: N-Q. Springer Berlin Heidelberg. pp. 274–. ISBN 978-3-642-65035-2.
- ^ Meyerson, Bengt J. (1967). "Relationship Between the Anesthetic and Gestagenic Action and Estrous Behavior-Inducing Activity of Different Progestins". Endocrinology. 81 (2): 369–374. ISSN 0013-7227. PMID 4952012. doi:10.1210/endo-81-2-369.
- ^ MARTINEZ MONTES EA, BAGNATI EP, ZAPATA AC, BUR GE (1960). "[Clinical trial of a new luteoid: norvinisterone]". Dia Med (in Spanish; Castilian). 32: 194–7. PMID 14421807.
- ^ Saunders, Francis J.; Drill, Victor A. (1956). "THE MYOTROPHIC AND ANDROGENIC EFFECTS OF 17-ETHYL-19-NORTESTOSTERONE AND RELATED COMPOUNDS". Endocrinology. 58 (5): 567–572. ISSN 0013-7227. PMID 13317831. doi:10.1210/endo-58-5-567.
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