Delmadinone acetate

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Delmadinone acetate
Delmadinone acetate.svg
Clinical data
ATCvet code
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEMBL
ECHA InfoCard 100.033.821
Chemical and physical data
Formula C23H27ClO4
Molar mass 402.911 g/mol
3D model (Jmol)

Delmadinone acetate (INN, USAN, BAN) (brand names Delmate, Estrex, Tardak, Tardastren, Tardastrex, Vetadinon, Zenadrex), sometimes abbreviated as DMA, and also known as 1,6-bisdehydro-6-chloro-17α-acetoxyprogesterone, is a steroidal progestin with antigonadotropic (and hence, antiandrogenic and antiestrogenic) properties which is used to treat androgen-associated conditions in veterinary medicine.[1][2][3] It must be used with care as it has the potential to cause adrenal insufficiency via inhibition of adrenocorticotropic hormone (ACTH) secretion from the pituitary gland.[4]

See also[edit]

References[edit]

  1. ^ F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 579. ISBN 978-0-412-46630-4. Retrieved 30 May 2012. 
  2. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 298. ISBN 978-3-88763-075-1. Retrieved 30 May 2012. 
  3. ^ Ian Morton; Judith M. Hall (1999). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer. p. 92. ISBN 978-0-7514-0499-9. Retrieved 30 May 2012. 
  4. ^ Court EA, Watson AD, Church DB, Emslie DR (August 1998). "Effects of delmadinone acetate on pituitary-adrenal function, glucose tolerance and growth hormone in male dogs". Australian Veterinary Journal. 76 (8): 555–60. doi:10.1111/j.1751-0813.1998.tb10216.x. PMID 9741725.