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IUPAC name
Other names
D-Galactitol; Dulcitol
608-66-2 YesY
3D model (Jmol) Interactive image
ChEBI CHEBI:16813 YesY
ChEMBL ChEMBL1773904 N
ChemSpider 11357 YesY
ECHA InfoCard 100.009.242
PubChem 11850
Molar mass 182.172 g/mol
-112.40·10−6 cm3/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Galactitol (dulcitol) is a sugar alcohol, the reduction product of galactose.[1] In people with galactokinase deficiency, a form of galactosemia, excess dulcitol forms in the lens of the eye leading to cataracts.[2]

Galactitol is produced from galactose in a reaction catalyzed by aldose reductase. Galactose itself comes from the metabolism of the disaccharide lactose into glucose and galactose.

The other common galactose metabolism defect is a defect in galactose-1-phosphate uridylyltransferase, an autosomal recessive disorder, which also causes a buildup of galactitol as a result of increased concentrations of galactose-1-phosphate and galactose. The toxicity associated with galactose-1-phosphate uridylyltransferase deficiency is associated with symptoms of hepatosplenomegaly and mental retardation in addition to the cataracts caused by galactitol buildup.


  1. ^ "Galactitol - Compound Summary". National Center for Biotechnology Information. Retrieved 2008-08-06. 
  2. ^ Roth, KS (September 10, 2007). "Galactokinase Deficiency". eMedicine. WebMD. Retrieved 2008-08-08.