Glycoside hydrolase family 1

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Glycosyl hydrolase family 1
PDB 1vff EBI.jpg
Identifiers
Symbol Glyco_hydro_1
Pfam PF00232
Pfam clan CL0058
InterPro IPR001360
PROSITE PDOC00495
SCOP 1cbg
SUPERFAMILY 1cbg
OPM superfamily 125
OPM protein 3gnr

Glycoside hydrolase family 1 is a family of glycoside hydrolases.

Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy(http://www.cazy.org/GH1.html) web site,[4] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[5]

Glycoside hydrolase family 1 CAZY GH_1 comprises enzymes with a number of known activities; beta-glucosidase (EC 3.2.1.21); beta-galactosidase (EC 3.2.1.23); 6-phospho-beta-galactosidase (EC 3.2.1.85); 6-phospho-beta-glucosidase (EC 3.2.1.86); lactase-phlorizin hydrolase (EC 3.2.1.62), lactase (EC 3.2.1.108); beta-mannosidase (EC 3.2.1.25); myrosinase (EC 3.2.1.147).

Subfamilies[edit]

Human proteins containing this domain[edit]

GBA3; KL; KLB; LCT; LCTL;

See also[edit]

GH1 in CAZypedia

References[edit]