Laminin subunit gamma-1

LAMC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1KLO, 1NPE, 1TLE, 4AQT
Identifiers
Aliases	LAMC1, LAMB2, Laminin, gamma 1, laminin subunit gamma 1
External IDs	OMIM: 150290; MGI: 99914; HomoloGene: 1724; GeneCards: LAMC1; OMA:LAMC1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	183,145,592 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	153,208,532 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; visceral pleura; ; parietal pleura; ; Achilles tendon; ; sural nerve; ; saphenous vein; ; placenta; ; gastric mucosa; ; urethra; ; synovial joint;
	Top expressed in
	ascending aorta; ; aortic valve; ; molar; ; left lung lobe; ; atrium; ; yolk sac; ; uterus; ; temporal muscle; ; sternocleidomastoid muscle; ; triceps brachii muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	extracellular matrix structural constituent; extracellular matrix constituent conferring elasticity;
Cellular component	extracellular matrix; extracellular region; basement membrane; laminin-1 complex; extracellular exosome; laminin-10 complex; laminin-11 complex; extracellular space; endoplasmic reticulum lumen; collagen-containing extracellular matrix;
Biological process	hemidesmosome assembly; substrate adhesion-dependent cell spreading; endoderm development; cell adhesion; extracellular matrix organization; cell migration; positive regulation of epithelial cell proliferation; extracellular matrix disassembly; post-translational protein modification; protein-containing complex assembly; animal organ morphogenesis; tissue development; organism system development; basement membrane assembly;
	Sources:Amigo / QuickGO
Orthologs
	3915
	226519
	ENSG00000135862
	ENSMUSG00000026478
	P11047
	P02468
	NM_002293
	NM_010683
	NP_002284
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Laminin subunit gamma-1 is a protein that in humans is encoded by the LAMC1 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135862 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026478 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fukushima Y, Pikkarainen T, Kallunki T, Eddy RL, Byers MG, Haley LL, Henry WM, Tryggvason K, Shows TB (May 1989). "Isolation of a human laminin B2 (LAMB2) cDNA clone and assignment of the gene to chromosome region 1q25----q31". Cytogenet Cell Genet. 48 (3): 137–41. doi:10.1159/000132610. PMID 3234037.
^ "Entrez Gene: LAMC1 laminin, gamma 1 (formerly LAMB2)".

References

Further reading