Laminin subunit gamma-2

LAMC2
Identifiers
Aliases	LAMC2, B2T, BM600, CSF, EBR2, EBR2A, LAMB2T, LAMNB2, Laminin, gamma 2, laminin subunit gamma 2, JEB3A, JEB3B
External IDs	OMIM: 150292; MGI: 99913; HomoloGene: 4062; GeneCards: LAMC2; OMA:LAMC2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	183,245,127 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	153,062,193 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; hair follicle; ; periodontal fiber; ; right uterine tube; ; lactiferous duct; ; pancreatic ductal cell; ; bronchial epithelial cell; ; visceral pleura; ; cervix epithelium; ; skin of abdomen;
	Top expressed in
	molar; ; corneal stroma; ; lung; ; lip; ; urinary bladder; ; stomach; ; colon; ; secondary oocyte; ; skin of back; ; urethra;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	heparin binding; extracellular matrix structural constituent;
Cellular component	laminin-2 complex; perinuclear region of cytoplasm; basement membrane; cell cortex; membrane; extracellular region; extracellular space; extracellular matrix; collagen-containing extracellular matrix;
Biological process	hemidesmosome assembly; cell adhesion; extracellular matrix organization; epidermis development; positive regulation of cell migration; positive regulation of cell population proliferation; organism system development; basement membrane assembly; animal organ morphogenesis; tissue development; cell migration; substrate adhesion-dependent cell spreading;
	Sources:Amigo / QuickGO
Orthologs
	3918
	16782
	ENSG00000058085
	ENSMUSG00000026479
	Q13753
	Q61092
	NM_018891; NM_005562
	NM_008485
	NP_005553; NP_061486
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Laminin subunit gamma-2 is a protein that in humans is encoded by the LAMC2 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000058085 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026479 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kallunki P, Sainio K, Eddy R, Byers M, Kallunki T, Sariola H, Beck K, Hirvonen H, Shows TB, Tryggvason K (Nov 1992). "A truncated laminin chain homologous to the B2 chain: structure, spatial expression, and chromosomal assignment". J Cell Biol. 119 (3): 679–93. doi:10.1083/jcb.119.3.679. PMC 2289671. PMID 1383240.
^ "Entrez Gene: LAMC2 laminin, gamma 2".

References

Further reading