1943 was dominated by a musicians' strike, which since August 1942 had prevented the recording of commercial music by the record companies. As the strike dragged on, the labels began releasing material from their artists' back catalogues, until by mid-1943, that ran out too. Okeh Records released Al Dexter's "Pistol Packin' Mama", backed with "Rosalita", in March. It sold quickly, helped by reports in Billboard magazine and great popularity in jukeboxes, which had run out of fresh material to play. Although Billboard did not publish its first Folk-Hillbilly chart until January 8, 1944, "Pistol Packin' Mama" became the first "Hillbilly" record to reach no. 1 on the National Best Selling Retail Records chart, on October 30, 1943,[8] and spent sixteen weeks in the top 10, on its way to selling 3 million copies.[9][10] It entered the Jukebox chart on July 31, 1943,[11] where it stayed for 28 weeks (the last 14 shared with the Bing Crosby version), another unheard of achievement for a "Hillbilly" tune. In Billboard's 1943 Yearbook, released in September, Dexter's "Pistol Packin' Mama" was the only hillbilly record to join Glenn Miller and Tommy Dorsey in the best-selling record list.[12]
Crosby, always a major fan of "hillbilly" music,[13] was finally able to record a cover version with the Andrews Sisters on September 27, when his label, Decca, became the first to settle with the union. The single, released on October 21, followed Dexter's to the top, revitalizing popularity and sales into 1944. When the first Billboard "Most Played Jukebox Folk Records" chart was published, both "Pistol Packin' Mama" versions tied for Number 1, and remained tied for seven straight weeks.[14]
The NBC radio network banned Crosby's version because of the line "drinking beer in a cabaret." The lyrics had to be changed to "singing songs in a cabaret" before it could air.[15][16]
The Irving Berlin song "You Can't Get a Man with a Gun", from the musical Annie Get Your Gun, contains the lyric: "A man's love is mighty, he'll even buy a nightie, for a gal who he thinks is fun. But they don't buy pajamas for pistol packin' mamas."
The chorus of the song was used for the 1970s UK television advertising campaign for Rowntree's Fruit Pastilles, with the punning tag line "Pastille Pickin' Mama, pass those pastilles round."[25]
It is also continually referenced in Spike Milligan's Goodbye Soldier (1986), which is part of his memoirs of World War II and just after it. In it he states that as Mussolini did not like jazz, after he was defeated the Italians were getting into jazz, and as this song was popular at the time, this was one of the songs Milligan and his group was often asked to sing. He also states that this is one of the main songs sung by Italian jazz bands (in fact he states that some bands only ever sang this song).
There is also a version of the song on an album titled A.P.C. Presents: The Unreleasable Tapes, with Bryan Adams being credited with the lead vocals.[26]
The Bing Crosby and Andrews Sisters version of the song is featured in the video games L.A. Noire and Fallout 4, on radio stations in-game, and in the episode "The Atomic Job" of Agent Carter.
A B17-G Flying Fortress named "Pistol Packin' Mama" was lost on July 20, 1944, on a mission to Leipzig.[27]
In episode #151 of Hee Haw, the whole Hee Haw Gang, led by Buck Owens, performed the song in front of the haystack.[28]
In a 1964 episode of the television program McHale's Navy entitled "The Rage of Taratupa", the song is sung several times by the character Harley Hatfield, played by actor Jesse Pearson.