Webb Miller

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For the Pulitzer Prize-winning war correspondent, see Webb Miller (journalist).
Webb Miller
Webb miller.jpg
Webb Colby Miller

1943 (age 76–77)
NationalityUnited States
Alma materUniversity of Washington
Known forBLAST
AwardsISCB Senior Scientist Award[1]
ISCB Fellow[2]
Scientific career
InstitutionsThe Pennsylvania State University
ThesisToward Abstract Numerical Analysis (1969)

Webb Colby Miller (born 1943) is a professor in the Department of Biology and the Department of Computer Science and Engineering at The Pennsylvania State University.[4][3]


Miller attended Whitman College, and received his Ph.D. in mathematics from the University of Washington in 1969.[5]

Research and career[edit]

He joined Penn State in September 1985. Prior to that, he had held a position as permanent staff member at the IBM Thomas J. Watson Research Center and served on the faculty at the University of California, Santa Barbara, and the University of Arizona. He is a fellow of ISCB (International Society for Computational Biology).

Miller has been developing algorithms and software for analyzing DNA sequences and related types of data from molecular genetics. He is one of the authors of BLAST.[6][7] He also develops methods for aligning long DNA sequences and extracting functional information from them. Webb Miller has made important contributions to the analysis of many vertebrate genomes. He is regarded as one of the pioneers in the field of computational biology.

Webb Miller's recent research interests[8][9] include the bioinformatics of species extinction, collaborating with Stephan Schuster, who is a Professor of Biochemistry and Molecular Biology at Penn State. In November 2008, they published a paper in Nature that described a draft sequence for the woolly mammoth genome.[10]


Miller was awarded the ISCB Senior Scientist Award[1] and elected an ISCB Fellow by the International Society for Computational Biology in 2009.[2] He is also among The 2009 Time 100.


  1. ^ a b Morrison Mckay, B. J.; Sansom, C. (2009). "Webb Miller and Trey Ideker to Receive Top International Bioinformatics Awards for 2009 from the International Society for Computational Biology". PLoS Computational Biology. 5 (4): e1000375. doi:10.1371/journal.pcbi.1000375. PMC 2666155. PMID 19390599.
  2. ^ a b Anon (2017). "ISCB Fellows". iscb.org. International Society for Computational Biology. Archived from the original on 2017-03-20.
  3. ^ a b Webb Miller publications indexed by Google Scholar Edit this at Wikidata
  4. ^ http://classify.oclc.org/classify2/ClassifyDemo?search-author-txt=%22Miller%2C+Webb+Colby%2C+1943-%22
  5. ^ Webb Miller at the Mathematics Genealogy Project
  6. ^ Altschul, S.; Gish, W.; Miller, W.; Myers, E.; Lipman, D. (1990). "Basic Local Alignment Search Tool". Journal of Molecular Biology. 215 (3): 403–410. doi:10.1016/S0022-2836(05)80360-2. PMID 2231712.
  7. ^ Altschul, S.; Madden, T. L.; Schäffer, A. A.; Zhang, J.; Zhang, Z.; Miller, W.; Lipman, D. J. (1997). "Gapped BLAST and PSI-BLAST: A new generation of protein database search programs". Nucleic Acids Research. 25 (17): 3389–3402. doi:10.1093/nar/25.17.3389. PMC 146917. PMID 9254694.
  8. ^ List of publications from Microsoft Academic[dead link]
  9. ^ Webb Miller at DBLP Bibliography Server Edit this at Wikidata
  10. ^ Miller, W.; Drautz, D. I.; Ratan, A.; Pusey, B.; Qi, J.; Lesk, A. M.; Tomsho, L. P.; Packard, M. D.; Zhao, F.; Sher, A.; Tikhonov, A.; Raney, B.; Patterson, N.; Lindblad-Toh, K.; Lander, E. S.; Knight, J. R.; Irzyk, G. P.; Fredrikson, K. M.; Harkins, T. T.; Sheridan, S.; Pringle, T.; Schuster, S. C. (2008). "Sequencing the nuclear genome of the extinct woolly mammoth" (PDF). Nature. 456 (7220): 387–390. doi:10.1038/nature07446. PMID 19020620.[permanent dead link]