Iflaviridae

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Iflaviridae
Virus classification
Group: Group IV ((+)ssRNA)
Order: Picornavirales
Family: Iflaviridae
Genera

Iflaviridae is a family of positive sense RNA viruses insect-infecting viruses. Some of the insects commonly infected by iflaviruses include aphids, leafhoppers, flies, bees, ants, silkworms and wasps. The name "Ifla" is derived from the name "Infectious flacherie virus", for the type species.[1]

Taxonomy[edit]

The family has a single genus, Iflavirus, which contains nine species: Infectious flacherie virus, the type species, Deformed wing virus, Ectropis obliqua virus, Lygus lineolaris virus 1, Nilaparvata lugens honeydew virus 1, Perina nuda virus, Sacbrood virus, Slow bee paralysis virus and Varroa destructor virus-1. Other viruses proposed by the ICTV's Picornavirales Study Group to fall within the family have not been assigned to a genus; as of February 2015, these are Antheraea pernyi iflavirus, Brevicoryne brassicae picorna-like virus, Dinocampus coccinellae paralysis virus, Halyomorpha halys virus, Heliconius erato iflavirus, Laodelphax striatellus picorna-like virus 2, Nasonia vitripennis virus, Spodoptera exigua iflavirus 1, Spodoptera exigua iflavirus 2, Thaumetopoea pityocampa iflavirus 1 and Venturia canescens picorna-like virus. Nick J. Knowles of the Picornavirales Study Group has suggested that ten of the viruses fall into seven subdivisions.[2]

Description[edit]

Members of this family are insect-infecting viruses that consist of positive single-strand RNA genomes translated into a single polyprotein of ~3000 amino acids long. It encodes helicase, protease and RNA-dependent RNA polymerase enzymes and four structural proteins (VP1–4). The non-enveloped capsid has an icosahedral T=3 symmetry and is around 30 nm in diameter. VP1, VP2 and VP3 form the outer portion, with VP4 located internally.[1][3]

Pathogenicity[edit]

Several viruses in this family are economically important because they are highly pathogenic to their honeybee and silkworm hosts, while others (including Dinocampus coccinellae paralysis virus, Nasonia vitripennis virus and Venturia canescens picorna-like virus) appear to cause little or no symptoms.[4]

References[edit]

  1. ^ a b ICTV Dicistroviridae Study Group (10 July 2002), Taxonomic Proposals from the ICTV Dicistroviridae Study Group (PDF), International Committee on Taxonomy of Viruses 
  2. ^ Picornavirales Study Group, Iflaviridae, retrieved 12 February 2015 
  3. ^ "Iflaviridae", ViralZone, retrieved 12 February 2015 
  4. ^ Dheilly NM, Maure F, Ravallec M et al., "Who is the puppet master? Replication of a parasitic wasp-associated virus correlates with host behaviour manipulation", Proceedings of the Royal Society B, doi:10.1098/rspb.2014.2773