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Aviv Regev

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Aviv Regev
Aviv Regev at the Intelligent Systems for Molecular Biology conference in 2017
Born1970's
Alma materTel Aviv University (Ph.D.)
Awards
Scientific career
FieldsBioinformatics
Computational Biology
Institutions
Doctoral advisorEva Jablonka
Ehud Shapiro
Websitewww.gene.com/scientists/our-scientists/aviv-regev Edit this at Wikidata

Aviv Regev is a computational biologist and Executive Vice President of Genentech Research and Early Development.[3] She was professor at the Broad Institute of MIT and Harvard and at the Department of Biology of the Massachusetts Institute of Technology,[4] as well as investigator at the Howard Hughes Medical Institute.[5] She and Sarah Teichmann lead the Human Cell Atlas project.[6]

Education

Regev studied at the Adi Lautman Interdisciplinary Program for Outstanding Students of Tel Aviv University, where she completed her Ph.D. under the supervision of Eva Jablonka[7] and Ehud Shapiro.[8]

Career and research

Regev is currently the Executive Vice President of Genentech Research and Early Development. She is based in South San Francisco.[9][10]

She served as the Core Institute Member, Chair of the Faculty and Co-director of the Cell Circuits Program at the Broad Institute.

Regev's highly cited[11][12] research includes work on gene expression[13][14] (with Eran Segal and David Botstein), and the use of π-calculus to represent biochemical processes.[15][16][17] Regev’s team has been a leading pioneer of single-cell genomics experimental and computational methods.[18]

Awards and honors

Regev was awarded the Overton Prize in 2008 for "outstanding accomplishment to a scientist in the early to mid stage of his or her career".[1] She was awarded the ISCB Innovator Award in 2017.[2][19] In 2008, she was also awarded the NIH Director's Pioneer Award.[20] She has also been awarded the Burroughs Wellcome Fund Career Award.[21] In 2017, she was awarded a Paul Marks Prize for Cancer Research.[22] She was elected a member of the National Academy of Sciences (NAS) in 2019.[23]She was awarded the 25th Keio Medical Science Prize in 2020.[24]

References

  1. ^ a b Sansom, C.; Morrison Mckay, B. J. (2008). Bourne, Philip E. (ed.). "ISCB Honors David Haussler and Aviv Regev". PLOS Computational Biology. 4 (7): e1000101. Bibcode:2008PLSCB...4E0101S. doi:10.1371/journal.pcbi.1000101. PMC 2536508. PMID 18795145.{{cite journal}}: CS1 maint: unflagged free DOI (link) Open access icon
  2. ^ a b Fogg, Christiana N.; Kovats, Diane E.; Berger, Bonnie (2017). "2017 ISCB Innovator Award: Aviv Regev". PLOS Computational Biology. 13 (6): e1005558. Bibcode:2017PLSCB..13E5558F. doi:10.1371/journal.pcbi.1005558. ISSN 1553-7358. PMC 5493285. PMID 28665936.{{cite journal}}: CS1 maint: unflagged free DOI (link) Open access icon
  3. ^ GENENTECH EXECUTIVE COMMITTEE, accessed August 6, 2020.
  4. ^ "Aviv Regev at MIT". biology.mit.edu.
  5. ^ "Aviv Regev, PhD: Investigator / 2014–Present". hhmi.org. Howard Hughes Medical Institute.
  6. ^ Nowogrodzki, Anna (5 July 2017). "How to build a human cell atlas". Nature. 547 (7661): 24–26. doi:10.1038/547024a. Retrieved 11 December 2020.
  7. ^ Regev, A.; Lamb, M. J.; Jablonka, E. (1998). "The Role of DNA Methylation in Invertebrates: Developmental Regulation or Genome Defense?". Molecular Biology and Evolution. 15 (7): 880. doi:10.1093/oxfordjournals.molbev.a025992. ISSN 0737-4038.
  8. ^ Regev, A.; Shapiro, E. (2002). "Cellular abstractions: Cells as computation". Nature. 419 (6905): 343. Bibcode:2002Natur.419..343R. doi:10.1038/419343a. PMC 3842595. PMID 12353013. Closed access icon
  9. ^ Taylor, Nick Paul (May 11, 2020). "Genentech lures Regev from Broad Institute to lead research and early development". fiercebiotech.com. Retrieved 25 May 2020.
  10. ^ "Changes to the Roche Enlarged Corporate Executive Committee" (Press release). Basel, Switzerland: F. Hoffmann-La Roche Ltd. globenewswire. May 11, 2020. Retrieved 2020-05-25.
  11. ^ "Aviv Regev publications in Google Scholar". scholar.google.com.
  12. ^ Search Results for author Regev A on PubMed.
  13. ^ Segal, E.; Shapira, M.; Regev, A.; Pe'er, D.; Botstein, D.; Koller, D.; Friedman, N. (2003). "Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data". Nature Genetics. 34 (2): 166–176. doi:10.1038/ng1165. PMID 12740579. S2CID 6146032.
  14. ^ Segal, E.; Friedman, N.; Koller, D.; Regev, A. (2004). "A module map showing conditional activity of expression modules in cancer". Nature Genetics. 36 (10): 1090–1098. doi:10.1038/ng1434. PMID 15448693. Closed access icon
  15. ^ Regev, A.; Silverman, W.; Shapiro, E. (2001). "Representation and simulation of biochemical processes using the pi-calculus process algebra". Pacific Symposium on Biocomputing: 459–470. doi:10.1142/9789814447362_0045. ISBN 978-981-02-4515-3. PMID 11262964.
  16. ^ Priami, C.; et al. (2001). "Application of a stochastic name-passing calculus to representation and simulation of molecular processes" (PDF). Information Processing Letters. 80: 25–31. doi:10.1016/S0020-0190(01)00214-9. Closed access icon
  17. ^ Study provides insight into regenerative potential of prostate gland, News Medical, accessed May 4, 2020.
  18. ^ "Aviv Regev". HHMI.org. Retrieved 2020-05-11.
  19. ^ "February 09, 2017: ISCB Announces 2017 Award Recipients". iscb.org. Retrieved 10 February 2017.
  20. ^ 2008 NIH Director’s Pioneer Award
  21. ^ Dynamic single-cell imaging of direct reprogramming reveals an early specifying event - Nature Biotechnology: Aviv Regev, Ph.D. - Career Awards at the Scientific Interface; Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs - Nature Biotechnology: Aviv Regev, Ph.D. - Career Awards at the Scientific Interface.
  22. ^ "2017 Prize Winners". Memorial Sloan Kettering Cancer Center. Retrieved 12 December 2017.
  23. ^ "2019 NAS Election". nasonline.org. Retrieved 30 April 2019.
  24. ^ "Award Ceremony for the 25th Keio Medical Science Prize". keio.ac.jp. Retrieved 22 December 2020.
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