CNTRL

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For the Electronic Dance Music educational initiative, see CNTRL: Beyond EDM.
CNTRL
Identifiers
Aliases CNTRL, CEP1, CEP110, FAN, bA165P4.1, centriolin
External IDs MGI: 1889576 HomoloGene: 38260 GeneCards: CNTRL
RNA expression pattern
PBB GE CEP110 205642 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007018
NM_001330762

NM_001290635
NM_012018
NM_030000

RefSeq (protein)

NP_001317691
NP_008949

NP_001277564
NP_036148

Location (UCSC) Chr 9: 121.07 – 121.18 Mb Chr 2: 35.11 – 35.18 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Centriolin is a protein that in humans is encoded by the CNTRL gene. It was previously known as CEP110.[3][4]

This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centriolin.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Guasch G, Mack GJ, Popovici C, Dastugue N, Birnbaum D, Rattner JB, Pebusque MJ (Mar 2000). "FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33)". Blood. 95 (5): 1788–96. PMID 10688839. 
  4. ^ a b "Entrez Gene: CEP110 centrosomal protein 110kDa". 

External links[edit]

Further reading[edit]