Collagen, type XIX, alpha 1

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COL19A1
Identifiers
AliasesCOL19A1, COL9A1L, D6S228E, collagen type XIX alpha 1, collagen type XIX alpha 1 chain
External IDsMGI: 1095415 HomoloGene: 55608 GeneCards: COL19A1
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for COL19A1
Genomic location for COL19A1
Band6q13Start69,866,571 bp[1]
End70,209,976 bp[1]
RNA expression pattern
PBB GE COL19A1 211011 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001858

NM_007733

RefSeq (protein)

NP_001849

NP_031759

Location (UCSC)Chr 6: 69.87 – 70.21 MbChr 1: 24.26 – 24.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Collagen alpha-1(XIX) chain is a protein that in humans is encoded by the COL19A1 gene.[5][6][7]

This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000082293 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026141 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Myers JC, Sun MJ, D'Ippolito JA, Jabs EW, Neilson EG, Dion AS (Mar 1993). "Human cDNA clones transcribed from an unusually high-molecular-weight RNA encode a new collagen chain". Gene. 123 (2): 211–7. doi:10.1016/0378-1119(93)90126-N. PMID 7916703. 
  6. ^ Gerecke DR, Olson PF, Koch M, Knoll JH, Taylor R, Hudson DL, Champliaud MF, Olsen BR, Burgeson RE (Jul 1997). "Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13". Genomics. 41 (2): 236–42. doi:10.1006/geno.1997.4638. PMID 9143499. 
  7. ^ a b "Entrez Gene: COL19A1 collagen, type XIX, alpha 1". 

Further reading[edit]