Collagen, type XII, alpha 1

COL12A1
Identifiers
Aliases	COL12A1, BA209D8.1, COL12A1L, DJ234P15.1, BTHLM2, UCMD2, collagen type XII alpha 1, collagen type XII alpha 1 chain, EDSMYP
External IDs	OMIM: 120320; MGI: 88448; HomoloGene: 3217; GeneCards: COL12A1; OMA:COL12A1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	75,206,267 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	79,626,113 bp
RNA expression pattern
	Top expressed in
	tibia; ; Achilles tendon; ; cartilage tissue; ; stromal cell of endometrium; ; skin of arm; ; pericardium; ; synovial joint; ; vulva; ; tail of epididymis; ; synovial membrane;
	Top expressed in
	body of femur; ; calvaria; ; umbilical cord; ; dermis; ; stroma of bone marrow; ; molar; ; vas deferens; ; human fetus; ; efferent ductule; ; external carotid artery;
	More reference expression data
	n/a
Gene ontology
Molecular function	extracellular matrix structural constituent conferring tensile strength;
Cellular component	extracellular vesicle; collagen type XII trimer; collagen; endoplasmic reticulum lumen; extracellular exosome; extracellular space; extracellular matrix; extracellular region; collagen-containing extracellular matrix;
Biological process	collagen catabolic process; skeletal system development; cell adhesion; endodermal cell differentiation; collagen fibril organization; growth plate cartilage chondrocyte morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	1303
	12816
	ENSG00000111799
	ENSMUSG00000032332
	Q99715
	Q60847
	NM_004370; NM_080645
	NM_001290308; NM_007730
	NP_004361; NP_542376
	NP_001277237
	Wikidata
View/Edit Human	View/Edit Mouse

Collagen alpha-1(XII) chain is a protein that in humans is encoded by the COL12A1 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000111799 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032332 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Gerecke DR, Olson PF, Koch M, Knoll JH, Taylor R, Hudson DL, Champliaud MF, Olsen BR, Burgeson RE (Jul 1997). "Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13". Genomics. 41 (2): 236–42. doi:10.1006/geno.1997.4638. PMID 9143499.
^ "Entrez Gene: COL12A1 collagen, type XII, alpha 1".

References

Further reading