Exo-1,4-beta-D-glucosaminidase
| Exo-1,4-beta-D-glucosaminidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.2.1.165 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Exo-1,4-beta-D-glucosaminidase (EC 3.2.1.165, CsxA, GlcNase, exochitosanase, GlmA, exo-beta-D-glucosaminidase, chitosan exo-1,4-beta-D-glucosaminidase) is an enzyme with systematic name chitosan exo-(1->4)-beta-D-glucosaminidase.[1][2][3]![4][5] This enzyme catalyses the following chemical reaction
- Hydrolysis of chitosan or chitosan oligosaccharides to remove successive D-glucosamine residues from the non-reducing termini
Chitosan is a partially or totally N-deacetylated chitin derivative that is found in the cell walls of some phytopathogenic fungi .
References
- ^ Nanjo, F.; Katsumi, R.; Sakai, K. (1990). "Purification and characterization of an exo-β-D-glucosaminidase, a novel type of enzyme, from Nocardia orientalis". J. Biol. Chem. 265: 10088–10094. PMID 2351651.
- ^ Nogawa, M.; Takahashi, H.; Kashiwagi, A.; Ohshima, K.; Okada, H.; Morikawa, Y. (1998). "Purification and characterization of exo-β-D-glucosaminidase from a cellulolytic fungus, Trichoderma reesei PC-3-7". Appl. Environ. Microbiol. 64: 890–895. PMID 16349528.
- ^ Fukamizo, T.; Fleury, A.; Côté, N.; Mitsutomi, M.; Brzezinski, R. (2006). "Exo-β-D-glucosaminidase from Amycolatopsis orientalis: catalytic residues, sugar recognition specificity, kinetics, and synergism". Glycobiology. 16: 1064–1072. doi:10.1093/glycob/cwl026. PMID 16877749.
- ^ Côté, N.; Fleury, A.; Dumont-Blanchette, E.; Fukamizo, T.; Mitsutomi, M.; Brzezinski, R. (2006). "Two exo-β-D-glucosaminidases/exochitosanases from actinomycetes define a new subfamily within family 2 of glycoside hydrolases". Biochem. J. 394: 675–686. doi:10.1042/bj20051436. PMID 16316314.
- ^ Ike, M.; Isami, K.; Tanabe, Y.; Nogawa, M.; Ogasawara, W.; Okada, H.; Morikawa, Y. (2006). "Cloning and heterologous expression of the exo-β-D-glucosaminidase-encoding gene (gls93) from a filamentous fungus, Trichoderma reesei PC-3-7". Appl. Microbiol. Biotechnol. 72: 687–695. doi:10.1007/s00253-006-0320-y. PMID 16636831.
External links
- Exo-1,4-beta-D-glucosaminidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)