Flugestone acetate

Flugestone acetate
Clinical data
Routes of; administration	Intravaginal
Identifiers
	IUPAC name [(8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11-hydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate;
CAS Number	2529-45-5;
PubChem CID	10476437;
ChemSpider	8651847;
UNII	X60881643X;
KEGG	D04235;
ChEMBL	ChEMBL2106773;
CompTox Dashboard (EPA)	DTXSID6046210 ;
ECHA InfoCard	100.017.979
Chemical and physical data
Formula	C23H31FO5
Molar mass	406.487643 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(C)=O;
	InChI InChI=1S/C23H31FO5/c1-13(25)22(29-14(2)26)10-8-17-18-6-5-15-11-16(27)7-9-20(15,3)23(18,24)19(28)12-21(17,22)4/h11,17-19,28H,5-10,12H2,1-4H3/t17-,18-,19-,20-,21-,22-,23-/m0/s1; Key:JKQQZJHNUVDHKP-FQJIPJFPSA-N;

Flugestone acetate (FGA) (INN, BAN) (brand names Chronogest, Chrono-Gest, Cronolone, Synchro-Mate, Gyncro-Mate; former developmental code names NSC-65411, SC-9880), or flurogestone acetate (USAN), also known as 17α-acetoxy-9α-fluoro-11β-hydroxyprogesterone, is a steroidal progestin of the 17α-hydroxyprogesterone group that is used in veterinary medicine as an intravaginal sponge preparation to synchronize estrus in ewes and goats.^[1]^[2]^[3]^[4]^[5]^[6] It was developed by G.D. Searle & Company in the 1960s.^[7]^[8]

References

^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 559. ISBN 978-1-4757-2085-3.
^ Dr. Ian Morton; I.K. Morton; Judith M. Hall (31 October 1999). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 122–. ISBN 978-0-7514-0499-9.
^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 451–. ISBN 978-3-88763-075-1.
^ Office of the Federal Register (U S ); U. s. Government Printing Office (29 May 2012). Code of Federal Regulations Title 21: Food and Drug Administration: Parts 500-599, Revised April 1, 2012. Government Printing Office. pp. 359–. ISBN 978-0-16-090718-0.
^ Robert S. Youngquist; Walter R. Threlfall (23 November 2006). Current Therapy in Large Animal Theriogenology. Elsevier Health Sciences. pp. 2640–. ISBN 1-4377-1340-8.
^ Virginia P. Studdert; Clive C. Gay; Douglas C. Blood (9 December 2011). Saunders Comprehensive Veterinary Dictionary. Elsevier Health Sciences. pp. 2673–. ISBN 0-7020-4744-9.
^ Animal Husbandry Research: Reports on Agricultural Industry. 1967. p. 60.
^ Dairy Science Handbook. Agriservices Foundation. 1971. p. 10.

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