Non-modulating essential hypertension

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Non-modulating essential hypertension

Non-modulating essential hypertension is a form of salt-sensitive hypertension, where sodium intake does not modulate either adrenal or renal vascular responses to angiotensin II. Individuals with this subset have been termed non-modulators.[1] They make up 25-30% of the hypertensive population.[2]


  1. ^ Williams, GH; Hollenberg, NK (1985). "Non-modulating essential hypertension: A subset particularly responsive to converting enzyme inhibitors". Journal of Hypertension Supplement. 3 (2): S81–7. PMID 3003304.
  2. ^ Kasper, Braunwald, Fauci et al. Harrison's Principles of Internal Medicine 16th, Edition. McGraw-Hill New York[page needed]