Phenolic acid

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Phenolic acids or phenolcarboxylic acids are types of aromatic acid compound. Included in that class are substances containing a phenolic ring and an organic carboxylic acid function (C6-C1 skeleton). There are several categories of phenolic acids including:


Phenolic acids can be found in many plant species. Their content in dried fruits can be high.

Natural phenols in horse grams (Macrotyloma uniflorum) are mostly phenolic acids, namely 3,4-dihydroxy benzoic, p-hydroxy benzoic, vanillic, caffeic, p-coumaric, ferulic, syringic and sinapinic acids.[1]

Phenolic acids can be found in mushroom Basidiomycetes species.[2] It is also a part of the humic substances, which are the major organic constituents of soil humus.

Many phenolic acids can be found in human urine.[3]


Immobilized Candida antarctica lipase can be used to catalyze the direct acetylation of flavonoids with phenolic acids.[4]

See also[edit]


  1. ^ Identification and quantification of phenolic acids in Macrotyloma uniflorum by reversed phase HPLC. Kawsar, S.M.A., E. Huq, N. Nahar and Y. Ozeki, Am. J. Plant Physiol., 3: 165-172, 2008, doi:10.3923/ajpp.2008.165.172
  2. ^ Barros, L.; Dueñas, M.; Ferreira, I. C.; Baptista, P.; Santos-Buelga, C. (June 2009). "Phenolic acids determination by HPLC–DAD–ESI/MS in sixteen different Portuguese wild mushrooms species". Food and Chemical Toxicology 47 (6): 1076–1079. doi:10.1016/j.fct.2009.01.039. PMID 19425182. 
  3. ^ Armstrong, M. D.; Shaw, K. N.; Wall, P. E. (January 1, 1956). "The phenolic acids of human urine. Paper chromatography of phenolic acids" (pdf). The Journal of Biological Chemistry 218: 293–303. PMID 13278337. 
  4. ^ Direct acylation of flavonoid glycosides with phenolic acids catalysed by Candida antarctica lipase B (Novozym 435®). David E. Stevenson, Reginald Wibisono, Dwayne J. Jensen, Roger A. Stanley and Janine M. Cooney, Enzyme and Microbial Technology, 3 October 2006, Volume 39, Issue 6, Pages 1236–1241, doi:10.1016/j.enzmictec.2006.03.006