Receptor tyrosine kinase-like orphan receptor
| receptor tyrosine kinase-like orphan receptor 1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | ROR1 | ||||||
| Alt. symbols | NTRKR1 | ||||||
| NCBI gene | 4919 | ||||||
| HGNC | 10256 | ||||||
| OMIM | 602336 | ||||||
| RefSeq | NM_005012 | ||||||
| UniProt | Q01973 | ||||||
| Other data | |||||||
| EC number | 2.7.10.1 | ||||||
| Locus | Chr. 1 p32-p31 | ||||||
| |||||||
| receptor tyrosine kinase-like orphan receptor 2 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | ROR2 | ||||||
| Alt. symbols | NTRKR2, BDB, BDB1 | ||||||
| NCBI gene | 4920 | ||||||
| HGNC | 10257 | ||||||
| OMIM | 602337 | ||||||
| RefSeq | NM_004560 | ||||||
| UniProt | Q01974 | ||||||
| Other data | |||||||
| Locus | Chr. 9 q22 | ||||||
| |||||||
In the field of molecular biology, receptor tyrosine kinase-like orphan receptors (RORs) are a family of tyrosine kinase receptors that are important in regulating skeletal and neuronal development, cell migration and cell polarity. ROR proteins can modulate Wnt signaling by sequestering Wnt ligands.[1]
References
- ^ Green JL, Kuntz SG, Sternberg PW (November 2008). "Ror receptor tyrosine kinases: orphans no more". Trends Cell Biol. 18 (11): 536–44. doi:10.1016/j.tcb.2008.08.006. PMID 18848778.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
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