From Wikipedia, the free encyclopedia
Jump to: navigation, search
Not to be confused with Bromperamole.
Structure of bromperidol.png
Systematic (IUPAC) name
Clinical data
AHFS/ International Drug Names
Legal status
Routes Oral
CAS number 10457-90-6 N
ATC code N05AD06
PubChem CID 2448
ChemSpider 2354 YesY
KEGG D01101 YesY
Chemical data
Formula C21H23BrFNO2 
Mol. mass 420.315 g/mol
 N (what is this?)  (verify)

Bromperidol (marketed as Bromidol, Bromodol) is a drug which is a butyrophenone derivative. It is a potent and long-acting neuroleptic, used as an antipsychotic in the treatment of schizophrenia. It was discovered at Janssen Pharmaceutica in 1966.

Medical Uses[edit]

Antipsychotic drugs such as Bromperidol have been used for treating patients with schizophrenia for many years. Long‐acting depot injections of these types of drugs are extensively used as a means of long‐term maintenance treatment.

Adverse Effects[edit]

The characteristics of the side-effects of bromperidol was investigated in 33 acutely exacerbated Schizophrenic patients. The most frequently observed side-effects were extrapyramidal symptoms. Acute dystonia developed in 10 of 33 patients, and the mean age was significantly lower (P < 0.05) in patients with dystonia (27.3 ± 6.2 years) than that in patients without dystonia (41.5 ± 12.9 years).


  • Poldinger W, Bures E, Haage H, Clinical study with bromperidol, a new butyrophenone derivative, Int Pharmacopsychiatry. 1977;12(1):20-4.
  • Dubinsky B, McGuire JL, Niemegeers CJ, Janssen PA, Weintraub HS, McKenzie BE, Bromperidol, a new butyrophenone neuroleptic: a review, Psychopharmacology (Berl). 1982;78(1):1-7.
  • Yasui-furukori, N., Kondo, T., & Ishida, M. (2002). The characteristics of side-effects of bromperidol in schizophrenic patients, (December 2000), 103–106.