Bromperidol

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Bromperidol
Structure of bromperidol.png
Systematic (IUPAC) name
4-[4-(4-bromophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)butan-1-one
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
?
Routes Oral
Identifiers
CAS number 10457-90-6 N
ATC code N05AD06
PubChem CID 2448
ChemSpider 2354 YesY
UNII LYH6F7I22E YesY
KEGG D01101 YesY
ChEMBL CHEMBL28218 YesY
Chemical data
Formula C21H23BrFNO2 
Molecular mass 420.315 g/mol
 N (what is this?)  (verify)

Bromperidol (marketed as Bromidol, Bromodol) is a butyrophenone derivative. It is a potent and long-acting neuroleptic, used as an antipsychotic in the treatment of schizophrenia. It was discovered at Janssen Pharmaceutica in 1966.

References[edit]

  • Poldinger W, Bures E, Haage H, Clinical study with bromperidol, a new butyrophenone derivative, Int Pharmacopsychiatry. 1977;12(1):20-4.
  • Dubinsky B, McGuire JL, Niemegeers CJ, Janssen PA, Weintraub HS, McKenzie BE, Bromperidol, a new butyrophenone neuroleptic: a review, Psychopharmacology (Berl). 1982;78(1):1-7.