Perafensine

Perafensine
Clinical data
ATC code	None;
Identifiers
	IUPAC name 1-phenyl-3-(1-piperazinyl)isoquinoline;
CAS Number	72444-62-3;
PubChem CID	3047830;
ChemSpider	2310140;
CompTox Dashboard (EPA)	DTXSID40222744 ;
Chemical and physical data
Formula	C19H19N3
Molar mass	289.374 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c1ccc(cc1)c2c3ccccc3cc(n2)N4CCNCC4;
	InChI InChI=1S/C19H19N3/c1-2-6-15(7-3-1)19-17-9-5-4-8-16(17)14-18(21-19)22-12-10-20-11-13-22/h1-9,14,20H,10-13H2; Key:BHHDTFRLKOTSKW-UHFFFAOYSA-N;

Perafensine (INN) (code name HR-459) is a drug which was investigated as an antidepressant but was never marketed.^[1] It has been reported to antagonize the effects of reserpine and to inhibit the reuptake of norepinephrine; whether it also affects the reuptake of serotonin or dopamine is unclear.^[2]

References

^ C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1585–. ISBN 978-0-412-46630-4.
^ Bondinell, WilliamE.; Kaiser, Carl (1982). "Chapter 5. Antidepressants". 17: 41–50. doi:10.1016/S0065-7743(08)60487-X. ISSN 0065-7743. {{cite journal}}: Cite journal requires |journal= (help)

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