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Venki Ramakrishnan

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Venkatraman Ramakrishnan
Born1952 (age 71–72)
Chidambaram, Tamil Nadu, India
CitizenshipUnited States
Alma materMaharaja Sayajirao University of Baroda
Ohio University
Known forStructure and function of the ribosome; macromolecular crystallography
AwardsLouis-Jeantet Prize for Medicine (2007)
Nobel Prize in Chemistry (2009)
Scientific career
FieldsBiochemistry and Biophysics
InstitutionsMRC Laboratory of Molecular Biology, Cambridge, England

Venkatraman "Venki" Ramakrishnan (Tamil: வெங்கட்ராமன் ராமகிருஷ்ணன்; born 1952 in Chidambaram, Tamil Nadu, India) is a structural biologist at the MRC Laboratory of Molecular Biology in Cambridge, England.[1] He received the 2009 Nobel Prize in Chemistry "for studies of the structure and function of the ribosome".[2]

Early life

Venkatraman Ramakrishnan was born in Chidambaram in Cuddalore district of Tamil Nadu, India.[3][4][5]

He moved to Baroda (Vadodara) in Gujarat state at the age of three, where he had his schooling, except for spending 1960-61 in Adelaide, Australia. Following his Pre-Science at the Maharaja Sayajirao University of Baroda, he did his undergraduate studies in the same university on a National Science Talent Scholarship, graduating with a B.Sc. in Physics in 1971. Immediately after graduation he moved to the U.S.A., where he obtained his Ph.D. in Physics from Ohio University in 1976.[6][7][8] He then spent two years studying biology as a graduate student at the University of California, San Diego while making a transition from theoretical physics to biology.[9]

Career

Ramakrishnan first began work on ribosomes as a postdoctoral fellow with Peter Moore at Yale..[10] He continued to work on ribosomes as a staff scientist at Brookhaven National Laboratory. In 1995 he moved to the University of Utah as a Professor of Biochemistry, and in 1999, he moved to his current position at the Medical Research Council Laboratory of Molecular Biology in Cambridge, England.

In 1999, Ramakrishnan's laboratory published a 5.5 Angstrom resolution structure of the 30S subunit. The following year, his laboratory determined the complete atomic structure of the 30S subunit of the ribosome and its complexes with several antibiotics. This was followed by studies that provided structural insights into the mechanism that ensures the fidelity of protein biosynthesis. More recently, his laboratory has determined the atomic structure of the whole ribosome in complex with its tRNA and mRNA ligands. Ramakrishnan is also known for his past work on histone and chromatin structure.

Honours

Ramakrishnan is a Fellow of the Royal Society, a member of EMBO and the U.S. National Academy of Sciences and a Fellow of Trinity College, Cambridge. He was awarded the 2007 Louis-Jeantet Prize for Medicine, the 2008 Heatley Medal of the British Biochemical Society and the 2009 Rolf-Sammet Professorship at the University of Frankfurt. In 2009, Ramakrishnan was awarded the Nobel Prize in Chemistry along with Thomas A. Steitz and Ada Yonath.[11]

Personal life

Ramakrishnan is married to Vera Rosenberry, an author and illustrator of children's books. He has a stepdaughter, Tania Kapka, who is a doctor in Oregon, and a son, Raman Ramakrishnan, who is a cellist in New York.[12]

References

  1. ^ "Venki Ramakrishnan". Laboratory of Molecular Biology. 2004. Retrieved 2009-10-07.
  2. ^ "Venki Ramakrishnan". Nobel Foundation. 2009. Retrieved 2009-10-14.
  3. ^ His father Prof CV Ramakrishnan himself was a academician and Biochemist of international repute. He was associated with Baroda University and Madras Medical Mission Chennai...a non profit organization for a long period of time and was instrumental in starting the Physician Assistant program in India at the Madras Medical Mission2009 Nobel Prize in Chemistry, Nobel Foundation.
  4. ^ "Common root: Tamil Nadu gets its third laureate". Times of India. TNN. 8 October 2009.
  5. ^ D. Ram Raj (October 8, 2009). "Venki was a studious kid". DNA India.
  6. ^ "Venkatraman Ramakrishnan: A profile". Times of India. Press Trust of India. 7 October 2009. Retrieved 2009-10-07.
  7. ^ "FACTBOX: Nobel chemistry prize - Who are the winners?". Reuters. Retrieved 2009-10-07.
  8. ^ Sonwalkar, Prasun (October 8, 2009). "Venkatraman Ramakrishnan wins Nobel for Chemistry". Press Trust of India. Retrieved 2009-10-07.
  9. ^ "Profile: Dr Venkatraman Ramakrishnan". Indian Express. Associated Press. 7 October 2009. Retrieved 2009-10-07.
  10. ^ "Analysis of neutron distance data". J. Mol. Biol.
  11. ^ "All Nobel Laureates in Chemistry". Nobel Foundation. Retrieved 2009-10-07.
  12. ^ Amit Roy (17-Oct-2009). "'Venki' makes light of India link - Winner says not to treat science like cricket; league of misses grows". The Telegraph. Retrieved 2009-10-17. {{cite news}}: Check date values in: |date= (help)
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