SoRI-9804
Names | |
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IUPAC name
N-Benzhydryl-2-phenylquinazolin-4-amine
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Other names
Benzhydryl-(2-phenyl-quinazolin-4-yl)-amine; 4-((Diphenylmethyl)amino)-2-phenylquinazoline
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Identifiers | |
3D model (JSmol)
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PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C27H21N3 | |
Molar mass | 387.486 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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SoRI-9804 is a positive allosteric modulator of dopamine transporters. Unlike others in its series & traditional DRI ligands, it inhibits the release of dopamine in addition to inhibiting the reuptake of released dopamine back into the transporter.[1]
See also
References
- ^ "Studies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine release". 329 (2). May 2009: 718–28. doi:10.1124/jpet.108.149088. PMC 2672863. PMID 19244097.
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