Chimerin 2

CHN2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1XA6
Identifiers
Aliases	CHN2, ARHGAP3, BCH, CHN2-3, RHOGAP3, chimerin 2
External IDs	OMIM: 602857; MGI: 1917243; HomoloGene: 31213; GeneCards: CHN2; OMA:CHN2 - orthologs
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	54,278,795 bp
RNA expression pattern
	n/a
	Top expressed in
	lobe of cerebellum; ; cerebellar vermis; ; seminiferous tubule; ; olfactory tubercle; ; spermatid; ; zygote; ; nucleus accumbens; ; lateral septal nucleus; ; pontine nuclei; ; interventricular septum;
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; metal ion binding; GTPase activator activity;
Cellular component	cytoplasm; cytosol; membrane;
Biological process	intracellular signal transduction; regulation of small GTPase mediated signal transduction; signal transduction; positive regulation of signal transduction; positive regulation of GTPase activity; regulation of GTPase activity;
	Sources:Amigo / QuickGO
Orthologs
	1124
	69993
	ENSG00000106069
	ENSMUSG00000004633
	P52757
	Q80XD1
NM_001039936; NM_001293069; NM_001293070; NM_001293071; NM_001293072;
	NM_001293073; NM_001293075; NM_001293076; NM_001293077; NM_001293078; NM_001293079; NM_001293080; NM_001293081; NM_004067; NM_001398427
	NM_001163640; NM_023543; NM_001311133; NM_001311134
NP_001035025; NP_001279998; NP_001279999; NP_001280000; NP_001280001;
	NP_001280002; NP_001280004; NP_001280005; NP_001280006; NP_001280007; NP_001280008; NP_001280009; NP_001280010; NP_004058
	NP_001157112; NP_001298062; NP_001298063; NP_076032
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-chimaerin is a protein that in humans is encoded by the CHN2 gene.^[4]^[5]

Template:PBB Summary

References

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000004633 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Leung T, How BE, Manser E, Lim L (Jun 1994). "Cerebellar beta 2-chimaerin, a GTPase-activating protein for p21 ras-related rac is specifically expressed in granule cells and has a unique N-terminal SH2 domain". J Biol Chem. 269 (17): 12888–92. PMID 8175705.
^ "Entrez Gene: CHN2 chimerin (chimaerin) 2".

References

Further reading