Snake venom factor V activator
| Snake venom factor V activator | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.21.95 | ||||||||
| CAS no. | 471269-12-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Snake venom factor V activator (EC 3.4.21.95) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- Fully activates human clotting factor V by a single cleavage at the Trp-Tyr-Leu-Arg1545-Ser-Asn-Asn-Gly bond.
This enzyme is present in venom of Vipera russelli.
References
- ^ Kisiel, W.; Canfield, W. (1981). "M. Snake venom proteases that activate blood-coagulation factor V". Methods Enzymol. 80: 275–285. doi:10.1016/s0076-6879(81)80024-9. PMID 7043192.
- ^ Tokunaga, F.; Nagasawa, K.; Tamura, S.; Miyata, T.; Iwanaga, S.; Kisiel, W. (1988). "The factor V-activating enzyme (RVV-V) from Russell's viper venom. Identification of isoproteins RVV-Vα, -Vβ and -Vγ and their complete amino acid sequences". J. Biol. Chem. 263: 17417–17481. PMID 3053712.
External links
- Snake+venom+factor+V+activator at the U.S. National Library of Medicine Medical Subject Headings (MeSH)