Enoxolone
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Enoxolone
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| Systematic (IUPAC) name | |
| (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)
-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo- 1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b- icosahydropicene-2-carboxylic acid |
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| Identifiers | |
| CAS number | |
| ATC code | D03 |
| PubChem | |
| Chemical data | |
| Formula | C30H46O4 |
| Mol. mass | 470.684 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Enoxolone (or glycyrrhetinic acid) is a cicatrizant. It is one of the major components of licorice herbage. It has some pharmacological properties including antiviral, antifungal and antibacterial activities[1][2][3][4].
[edit] References
- The Merck Index, 12th Edition. 3628
- ^ Badam, L., Amagaya, S. and Pollard, B. (1997). "In vitro activity of licorice and glycyrrhetinic acid on Japanese encephalitis virus.". J. Community Dis. 29: 91-99.
- ^ Fuji, H.Y., Tian, J. and Luka, C. (1986). "Effect of glycyrrhetinic acid on influenza virus and pathogenic bacteria.". Bull. Chin. Mater. Med. 11: 238-241.
- ^ Guo, N., Takechi, M. and Uno, C. (1991). "Protective effects of glycyrrhetinic acid in mice with systhemic Candida albicans infection and it’s mechanism.". J. Pharm. Pharmacol. 12: 380 -383.
- ^ Salari, M. H., Sohrabi, N., Kadkhoda, Z., and Khalili, M. B. (2003). "Antibacterial effects of Enoxolone on periodontopathogenic and capnophilic bacteria isolated from specimens of periodontitis patients". Iran. Biomed. J. 7: 39-42.
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