Eric F. Wieschaus

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Eric Francis Wieschaus
Wieschaus ecal2011.jpg
Eric F. Wieschaus
Born (1947-06-08) June 8, 1947 (age 67)
South Bend, Indiana
Nationality American
Fields developmental biologist
Institutions Princeton University
Robert Wood Johnson Medical School
Alma mater University of Notre Dame (B.S.)
Yale University (Ph.D.)
Known for embryogenesis
Notable awards Genetics Society of America Medal (1995)
Nobel Prize in Physiology or Medicine (1995)

Eric Francis Wieschaus (born June 8, 1947 in South Bend, Indiana) is an American developmental biologist and 1995 Nobel Prize-winner.

Born in South Bend, Indiana, he attended John Carroll Catholic High School in Birmingham, AL before attending the University of Notre Dame for his undergraduate studies (B.S., biology), and Yale University (Ph.D., biology) for his graduate work. In 1978, he moved to his first independent job, at the European Molecular Biology Laboratory in Heidelberg, Germany and moved from Heidelberg to Princeton University in the United States in 1981.

Much of his research has focused on embryogenesis in the fruit fly Drosophila melanogaster, specifically in the patterning that occurs in the early Drosophila embryo. Most of the gene products used by the embryo at these stages are already present in the unfertilized egg and were produced by maternal transcription during oogenesis. A small number of gene products, however, are supplied by transcription in the embryo itself. He has focused on these "zygotically" active genes because he believes the temporal and spatial pattern of their transcription may provide the triggers controlling the normal sequence of embryonic development.

Saturation of all the possible mutations on each chromosome by random events to test embryonic lethality was done by Eric Wieschaus.(PSY IITK)

In 1995, he was awarded the Nobel Prize in Physiology or Medicine with Edward B. Lewis and Christiane Nüsslein-Volhard as co-recipients, for their work revealing the genetic control of embryonic development.

As of 2005, Wieschaus is the Squibb Professor in Molecular Biology at Princeton, and Adjunct Professor of Biochemistry at the University of Medicine and Dentistry of New JerseyRobert Wood Johnson Medical School.

He has three daughters and is married to molecular biologist Gertrud Schüpbach, who is also a professor of Molecular Biology at Princeton University, working on Drosophila oogenesis.

References[edit]

  • Gruenbaum, J (1996), "[Nobel prize winners in medicine--1995]", Harefuah (June 2, 1996) 130 (11): 746–8, PMID 8794677 
  • Blum, H E (1995), "[The 1995 Nobel Prize for medicine]", Dtsch. Med. Wochenschr. (December 22, 1995) 120 (51–52): 1797–800, doi:10.1055/s-0029-1234219, PMID 8549267 
  • Molven, A (1995), "[1995 Nobel Prize in physiology and medicine. The mystery of fetal development]", Tidsskr. Nor. Laegeforen. (December 10, 1995) 115 (30): 3712–3, PMID 8539733 
  • Connor, S (1995), "Nobel prize given for work on fruit flies", BMJ (October 21, 1995) 311 (7012): 1044, PMID 7580653 
  • Cohen, B (1995), "Nobel committee rewards pioneers of development studies in fruitflies", Nature (October 12, 1995) 377 (6549): 465, doi:10.1038/377465a0, PMID 7566128 

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