E. Donnall Thomas
|E. Donnall Thomas|
|Born||Edward Donnall Thomas
March 15, 1920
Mart, Texas, United States
|Died||October 20, 2012
Seattle, Washington, United States
|Institutions||Mary Imogene Bassett Medical Center|
|Alma mater||University of Texas at Austin
Harvard Medical School
|Notable awards||Nobel Prize in Physiology or Medicine,
National Medal of Science in 1990
Edward Donnall "Don" Thomas (March 15, 1920 – October 20, 2012) was an American physician, professor emeritus at the University of Washington, and director emeritus of the clinical research division at the Fred Hutchinson Cancer Research Center. In 1990 he shared the Nobel Prize in Physiology or Medicine with Joseph E. Murray for the development of cell and organ transplantation. Thomas developed bone marrow transplantation as a treatment for leukemia.
Thomas attended the University of Texas at Austin where he studied chemistry and chemical engineering, graduating with a B.A. in 1941 and an M. A. in 1943. While Thomas was an undergraduate he met his wife, Dorothy (Dottie) Martin while she was training to be journalist. They had three children. Thomas entered Harvard Medical School in 1943, receiving an M.D. in 1946. Dottie became a lab technician during this time to support the family, and the pair worked closely thereafter. He did his residency at Peter Bent Brigham Hospital before joining the US Army. "In 1955, he was appointed physician in chief at the Mary Imogene Bassett Hospital, now Bassett Medical Center, in Cooperstown, N.Y., an affiliate of Columbia University." 
At Mary Imogene Bassett, he began to study rodents that received lethal doses of radiation who were then saved by an infusion of marrow cells. At the time, patients who underwent bone marrow transplantation all died from infections or immune reactions that weren't seen in the rodent studies. Thomas began to use dogs as a model system. In 1963, he moved his lab to the United States Public Health Service in Seattle.
- Appelbaum, F. R. (2012). "E. Donnall Thomas (1920-2012)". Science 338 (6111): 1163–1163. doi:10.1126/science.1232395. PMID 23197524.
- "E. Donnall Thomas, Who Advanced Bone Marrow Transplants, Dies at 92". The New York Times. October 24, 2012.
- Storb, R. (2012). "Edward Donnall Thomas (1920–2012)". Nature 491 (7424): 334. doi:10.1038/491334a. PMID 23151572.
- "Notable Signers". Humanism and Its Aspirations. American Humanist Association. Retrieved October 4, 2012.
- Fred Hutchinson Research Center. Nobel Prize: The Don and Dottie Story
- Nobel Prize in Physiology or Medicine, 1990