Cortisone acetate: Difference between revisions
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'''Cortisone acetate''' (brand names '''Adreson''', '''Cortison''', '''Cortisone''', '''Cortisone Acetate''', '''Cortone''', '''Cortistab''', '''Cortisyl''', others) is a [[synthetic compound|synthetic]] [[glucocorticoid]] [[corticosteroid]] and [[corticosteroid ester]] which is marketed in many countries throughout the world, including in the [[United States]], the [[United Kingdom]], and various other [[Europe]]an countries.<ref name="Elks2014">{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA317|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=317–}}</ref><ref name="IndexNominum2000">{{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA276|year=2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=276–}}</ref><ref name="MortonHall2012">{{cite book|author1=I.K. Morton|author2=Judith M. Hall|title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms|url=https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA85|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-011-4439-1|pages=85–}}</ref> It is the C21 [[acetate]] [[ester]] of [[cortisone]],<ref name="Elks2014" /><ref name="IndexNominum2000" /> and acts as a [[prodrug]] of cortisone in the body.<ref name="pmid14640913">{{cite journal | vauthors = Løvås K, Husebye ES | title = Replacement therapy in Addison's disease | journal = Expert Opin Pharmacother | volume = 4 | issue = 12 | pages = 2145–9 | year = 2003 | pmid = 14640913 | doi = 10.1517/14656566.4.12.2145 | s2cid = 37628998 }}</ref> |
'''Cortisone acetate''' (brand names '''Adreson''', '''Cortison''', '''Cortisone''', '''Cortisone Acetate''', '''Cortone''', '''Cortistab''', '''Cortisyl''', others) is a [[synthetic compound|synthetic]] [[glucocorticoid]] [[corticosteroid]] and [[corticosteroid ester]] which is marketed (under prescription) in many countries throughout the world, including in the [[United States]], the [[United Kingdom]], and various other [[Europe]]an countries.<ref name="Elks2014">{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA317|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=317–}}</ref><ref name="IndexNominum2000">{{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA276|year=2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=276–}}</ref><ref name="MortonHall2012">{{cite book|author1=I.K. Morton|author2=Judith M. Hall|title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms|url=https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA85|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-011-4439-1|pages=85–}}</ref> It is the C21 [[acetate]] [[ester]] of [[cortisone]],<ref name="Elks2014" /><ref name="IndexNominum2000" /> and acts as a [[prodrug]] of cortisone in the body.<ref name="pmid14640913">{{cite journal | vauthors = Løvås K, Husebye ES | title = Replacement therapy in Addison's disease | journal = Expert Opin Pharmacother | volume = 4 | issue = 12 | pages = 2145–9 | year = 2003 | pmid = 14640913 | doi = 10.1517/14656566.4.12.2145 | s2cid = 37628998 }}</ref> |
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==References== |
==References== |
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Revision as of 03:37, 2 October 2022
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| Clinical data | |
|---|---|
| Trade names | Adreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others |
| Other names | Cortisone 21-acetate; 17α,21-Dihydroxypregn-4-ene-3,11,20-trione 21-acetate |
| Drug class | Corticosteroid; Glucocorticoid |
| Identifiers | |
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| CAS Number | |
| PubChem CID | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.000.006 |
| Chemical and physical data | |
| Formula | C23H30O6 |
| Molar mass | 402.487 g·mol−1 |
| 3D model (JSmol) | |
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Cortisone acetate (brand names Adreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others) is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed (under prescription) in many countries throughout the world, including in the United States, the United Kingdom, and various other European countries.[1][2][3] It is the C21 acetate ester of cortisone,[1][2] and acts as a prodrug of cortisone in the body.[4]
References
- ^ a b J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 317–. ISBN 978-1-4757-2085-3.
- ^ a b Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 276–. ISBN 978-3-88763-075-1.
- ^ I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 85–. ISBN 978-94-011-4439-1.
- ^ Løvås K, Husebye ES (2003). "Replacement therapy in Addison's disease". Expert Opin Pharmacother. 4 (12): 2145–9. doi:10.1517/14656566.4.12.2145. PMID 14640913. S2CID 37628998.
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