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Folliculitis

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Folliculitis
Folliculitis, single lesion
SpecialtyDermatology

Folliculitis is the infection and inflammation of one or more hair follicles. The condition may occur anywhere on hair-covered skin. The rash may appear as pimples that come to white tips on the face, chest, back, arms, legs, buttocks, or head.[1]

Although acne can often involve superficial infection and inflammation of some hair follicles, the condition of those follicles is usually not called folliculitis, as that term is usually reserved for the separate set of disease entities comprising infected and inflamed hair follicles with causes other than acne.

Signs and symptoms

Histopathology of folliculitis of unknown cause, with giant cells surrounding a hair follicle

Complications

This condition can develop into a more severe skin condition, such as cellulitis or abscess.[1]

Causes

Most carbuncles, boils, and other cases of folliculitis are infected with Staphylococcus aureus.[1]

Folliculitis starts with the introduction of a skin pathogen to a hair follicle. Hair follicles can also be damaged by friction from clothing, an insect bite,[2] blockage of the follicle, shaving, or braids that are very tight and close to the scalp. The damaged follicles are then infected by Staphylococcus spp. Folliculitis can affect people of all ages.[citation needed] Iron-deficiency anemia is sometimes associated with chronic cases.[citation needed]

Bacterial

  • Staphylococcus aureus folliculitis[1]
  • Hot-tub folliculitis is caused by the bacterium Pseudomonas aeruginosa.[3] The folliculitis usually occurs after sitting in a hot tub that was not properly cleaned before use. Symptoms are found around the body parts that sit in the hot tub - the legs, hips, chest, buttocks, and surrounding areas. Symptoms are amplified around regions that were covered by wet clothing, such as bathing suits.
  • Sycosis vulgaris, sycosis barbae, or barber's itch is a staphylococcal infection of the hair follicles in the bearded area of the face, usually the upper lip. Shaving aggravates the condition.
  • Gram-negative folliculitis may appear after prolonged acne treatment with antibiotics.[4]

Fungal

Mites

  • Demodex folliculitis is usually caused by an overgrowth of Demodex folliculorum a mite that lives in human hair follicles. Although most people with D. folliculorurm have no symptoms, the mite can reproduce excessively, particularly in people with oily scalps.

Viral

  • Herpetic folliculitis is rarer, but may occur when herpes simplex virus infection spreads to nearby hair follicles appearing in groups or clusters,[1] mostly around the mouth.

Noninfectious

  • Pseudofolliculitis barbae is a disorder occurring when hair curves back into the skin and causes inflammation.
  • Eosinophilic folliculitis may appear in persons with impaired immune systems.
  • Folliculitis decalvans or tufted folliculitis usually affects the scalp. Several hairs arise from the same hair follicle. Scarring and permanent hair loss may follow. The cause is unknown.
  • Folliculitis keloidalis scarring on the nape of the neck is most common among males with curly hair.
  • Oil folliculitis is inflammation of hair follicles due to exposure to various oils, and typically occurs on forearms or thighs. It is common in refinery workers, road workers, mechanics, and sheep shearers. Even makeup may cause it.
  • Malignancy may also be represented by recalcitrant cases.[5]

Treatment

Most simple cases resolve on their own, but first-line treatments are typically topical medications.[1]

  1. Topical antiseptic treatment is adequate for most cases.
  2. Topical antibiotics, such as mupirocin or neomycin/polymyxin B/bacitracin ointment may be prescribed. Oral antibiotics may also be used.
  3. Some patients may benefit from systemic narrow-spectrum penicillinase-resistant penicillins (such as dicloxacillin in the US or flucloxacillin in UK).
  4. Fungal folliculitis may require an oral antifungal such as fluconazole. Topical antifungals such as econazole nitrate may also be effective.[1]

Folliculitis may recur even after symptoms have gone away.[citation needed]

See also

References

  1. ^ a b c d e f g h Winters RD, Mitchell M (18 September 2019). "Folliculitis". Folliculitis in StatPearls. StatPearls. PMID 31613534.
  2. ^ "NHS Direct". 19 October 2017.
  3. ^ MedlinePlus Encyclopedia: Hot tub folliculitis
  4. ^ "Severe Acne: 4 types". American Academy of Dermatology. Archived from the original on February 9, 2011. Retrieved December 15, 2010.
  5. ^ Folliculitis, follicular mucinosis, and papular mucinosis as a presentation of chronic myelomonocytic leukemia. Rashid R, Hymes S. Dermatol Online J. 2009 May 15;15(5):16.